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Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

New treatments for male hypogonadism are effective and should be personalized.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Tinea capitis is a common scalp infection causing hair loss, mostly in young children.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.