April 2017 in “Journal of Investigative Dermatology” This study found that 10% carbamide peroxide significantly reduced acne lesions compared to a vehicle solution, suggesting it as an effective and safe alternative to benzoyl peroxide for treating mild to moderate acne.
January 2025 in “International Journal Of Scientific Advances” In this study using a rat model, researchers observed that applying topical testosterone led to changes in the skin resembling early acne lesions, indicating a dermatologic risk potentially associated with over-the-counter testosterone products.
2 citations
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September 2021 This review discusses the role of teledermatology during the COVID-19 pandemic, highlighting the practical challenges and opportunities in diagnosing skin diseases in low-income countries, and reports no new clinical results.
59 citations
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October 2016 in “Clinics in dermatology” This review discusses various sampling methods for studying Propionibacterium acnes in skin follicles and reports no new experimental results; the authors evaluate these methods' strengths and limitations.
11 citations
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January 1998 in “Dermatology” This study observed that isotretinoin was effective in treating acneiform eruptions in HIV-positive women, although side effects like skin xerosis and hair loss were reported.
May 2025 in “Lasers in Surgery and Medicine” This study reported that nonablative monopolar radiofrequency therapy provided sustained reductions in both inflammatory and noninflammatory acne lesion counts and sebum production in participants with moderate-to-severe acne vulgaris, with high patient satisfaction and no significant adverse effects observed up to 12 months posttreatment.
57 citations
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August 1995 in “British Journal of Dermatology” In this study, acne severity in females was strongly associated with inflammatory lesion count and moderately associated with androgens, especially DELTA 4 and DHEAS promoting acne and SHBG reducing it.
2 citations
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October 2021 in “Journal of Cosmetic Dermatology” In this randomized trial, the researchers observed that both montelukast and finasteride effectively reduced acne severity and lesion count in women with moderate acne, but finasteride showed greater efficacy. Both medications had transient, non-serious side effects, indicating satisfactory tolerability and safety.
October 2024 in “Cochrane library” This review examined evidence on non-systemic treatments for acne vulgaris and related skin complications, finding very low-certainty evidence that benzoyl peroxide may reduce lesion counts but may also increase the risk of minor adverse events, highlighting the need for higher-quality research for effective therapies.
6 citations
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February 2023 in “Journal of nanobiotechnology” In this study, HA-P5, a nanoparticle derived from peptide and polysaccharide conjugation, effectively reduced acne lesions and sebum production by inhibiting specific receptors in cells, without triggering unfavorable reactions compared to a commercial inhibitor, highlighting HA-P5's potential as a novel acne treatment.
January 2024 in “RSC pharmaceutics” This source discusses using stratum corneum ablation as a promising method to enhance transdermal drug delivery by temporarily removing the skin's outermost barrier to improve medication absorption.
January 2012 in “The Year book of dermatology” This study found that women with late onset acne have fewer comedones and acne lesions compared to those with early onset, despite no differences in P. acnes density or sebum secretion.
19 citations
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October 2017 in “Dermatologic Surgery” In this study, 755-nm alexandrite laser treatment significantly reduced acne keloidalis nuchae lesions in male patients, improving quality of life and showing low recurrence rates, with temporary hair loss as a reversible complication.
3 citations
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August 2024 in “Clinical Cosmetic and Investigational Dermatology” In this study, researchers found that specific treatment parameters disrupted follicles and sebaceous glands, damaging the bacteria Cutibacterium acnes and promoting follicular remodeling, which may improve both inflammatory and noninflammatory acne lesions.
1 citations
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August 2023 in “Clinical, Cosmetic and Investigational Dermatology” In this study, researchers observed that a hidden scalp condition could contribute to acne keloidalis nuchae and potentially other primary cicatricial alopecias, impacting their diagnosis and treatment.
December 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In this integrative literature review, the researchers reported that finasteride appears highly effective for treating androgenetic alopecia and acne, showing notable benefits after brief treatment durations, though careful dose management is required due to potential sexual side effects.
September 2022 in “Journal of the American Academy of Dermatology” The serum reduces acne and improves skin clarity.
10 citations
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January 2017 in “Expert Opinion on Pharmacotherapy” This review discusses the clinical features and treatment options for adult acne, highlighting the need for tailored management in specific populations, but reports no new findings.
1 citations
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June 1999 in “American Journal of Contact Dermatitis” In this study, tazarotene 0.1% gel showed greater efficacy than tretinoin 0.025% gel in reducing acne lesions and demonstrated similar efficacy to adapalene 0.1% gel when used less frequently.
24 citations
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March 2015 in “Dermatologic Surgery” This review discusses the modest efficacy of home-use laser and light devices for conditions like hair removal and acne, noting limited evidence and a lack of robust trials.
8 citations
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November 2020 in “Optics and Laser Technology” This review discusses the applications and advantages of LED-based photobiomodulation therapy for dermatological and cosmetic purposes but highlights existing challenges and health concerns while exploring future perspectives.
1 citations
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June 2013 in “Medicine” This article reviews how to take a thorough dermatological history, conduct examinations, and discusses diagnostic tools; it reports no new clinical findings.
6 citations
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November 1993 in “Contact dermatitis” Spironolactone in anti-acne cream can cause allergic skin reactions in some people.
29 citations
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March 2017 in “International Journal of Women's Dermatology” This review found that combined oral contraceptives and spironolactone are effective treatments for adult acne in women, but noted that oral contraceptives increase the risk of venous thromboembolism and require individual risk assessment before use.
118 citations
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May 2015 in “European journal of pharmaceutics and biopharmaceutics” This study found that the pH-sensitive hydrogel HECHA13, containing isoliquiritigenin, effectively inhibited the growth of Propionibacterium acnes and showed promise for transdermal delivery in acne treatment.
research Acne
2 citations
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May 2011 in “Harper's Textbook of Pediatric Dermatology” Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
37 citations
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January 2013 in “Postepy Dermatologii I Alergologii” This article discusses isotretinoin for severe acne vulgaris, noting its effectiveness but also highlighting significant side effects on skin, mucous membranes, and hair; it reports no new clinical results.
175 citations
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April 1982 in “Journal of The American Academy of Dermatology” This study found that oral isotretinoin achieved good to excellent clinical results in treating severe inflammatory acne, severe rosacea, and gram-negative folliculitis.
January 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study reports that an intervention decreased glucose and insulin levels, indicating improved insulin resistance, which is linked to a skin condition called acne vulgaris and other disorders associated with insulin resistance.
January 2011 in “Yearbook of Dermatology and Dermatologic Surgery” The adapalene-benzoyl peroxide gel works better and faster for acne treatment than using either ingredient alone, with manageable side effects.