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    Glossary Acetyl-L-carnitine

    naturally occurring compound aiding energy production and cognitive function

    Acetyl-L-carnitine (ALCAR) is a naturally occurring compound in the body that plays a crucial role in energy production by transporting fatty acids into the mitochondria, where they are burned for energy. It is also known for its potential neuroprotective effects and is often used as a dietary supplement to support cognitive function, improve mood, and enhance physical performance.

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    1. Decline of life’s energy theory of ageing 1. Revitalisation of energy metabolism and ageing mitochondria Expert Opinion on Therapeutic Patents · 2000 · 1 citations
    2. Dietary Supplements in Chemotherapy-Induced Peripheral Neuropathy: A New Hope? Nutrients · 2022 · 18 citations
    3. Research-based findings on scope of liposome-based cosmeceuticals: an updated review Future Journal of Pharmaceutical Sciences · 2022 · 13 citations
    4. G.P.2.16 Valproate, acetylcarnitine, folic acid and vitamin B12 in spinal muscular atrophy: Preliminary data of an open-label study in children Neuromuscular disorders · 2007 · 1 citations
    5. The interplay of oxidative stress and immune dysfunction in Hashimoto’s thyroiditis and polycystic ovary syndrome: a comprehensive review Frontiers in Immunology · 2023 · 1 citations
    6. Genetically Altered Expression of Spermidine/Spermine N1-Acetyltransferase Affects Fat Metabolism in Mice via Acetyl-CoA Journal of Biological Chemistry · 2006 · 128 citations
    7. Blockade of Androgen Markers Using a Novel Betasitosterol, Thioctic Acid and Carnitine-containing Compound in Prostate and Hair Follicle Cell-based Assays Phytotherapy Research · 2016 · 3 citations
    8. Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid and Saw Palmetto Extract Evidence-based Complementary and Alternative Medicine · 2009 · 22 citations
    9. Mechanisms of Puerariae Lobatae Radix in regulating sebaceous gland secretion: insights from network pharmacology and experimental validation Frontiers in Pharmacology · 2024 · 3 citations
    10. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism bioRxiv (Cold Spring Harbor Laboratory) · 2026
    11. Oxidative stress in ageing of hair International Journal of Trichology · 2009 · 126 citations
    12. Biology of hair pigmentation and its role in premature canities Pigment International · 2017 · 15 citations
    13. A Systematic Review of the Mechanisms and Therapeutic Applications of GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper Complex) in Topical Microneedle Delivery: A Case for Expanded Clinical Trials Archives of Internal Medicine Research · 2026
    14. From Diospyros kaki L. (Persimmon) Phytochemical Profile and Health Impact to New Product Perspectives and Waste Valorization Nutrients · 2021 · 43 citations
    15. Metabolic Engineering of Microorganisms to Produce L-Aspartate and Its Derivatives Fermentation · 2023
    16. Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing International Journal of Molecular Sciences · 2022 · 68 citations
    17. Metabolomic and lipidomic atlas of human hair across its length Communications Biology · 2025
    18. Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions Cell Proliferation · 2021 · 7 citations
    19. Methylmalonic Acidemia: Can Treatment be Improved? Journal of Nutritional Therapeutics · 2015
    20. Noval advance of histone modification in inflammatory skin diseases and related treatment methods Frontiers in immunology · 2024
    21. Biotinidase deficiency characterized by skin and hair findings Clinics in Dermatology · 2020 · 10 citations
    22. Plant Extracts in Skin Care Products 2018 · 5 citations
    23. A REVIEW ON PALITYA AND DHATRYADI RASAYANA International journal of research in ayurveda and pharmacy · 2023
    24. Sperm aneuploidy in infertile male patients: a systematic review of the literature Andrologia · 2014 · 26 citations
    25. New lifestyle drugs and somatoform disorders in dermatology Journal of The European Academy of Dermatology and Venereology · 2007 · 14 citations
    26. Mesotherapy: myth and reality Expert Review of Dermatology · 2011 · 3 citations
    27. Side effects of mesotherapy - review Journal of Education Health and Sport · 2023 · 2 citations
    28. Aging and Anti-Aging in Hair and Hair Loss Elsevier eBooks · 2013 · 1 citations
    29. Lifestyle Drugs in Old Age – A Mini-Review Gerontology · 2008 · 1 citations
    30. Signaling pathways and targeted therapeutic strategies for polycystic ovary syndrome Frontiers in endocrinology · 2023