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November 1996 in “Journal of Cutaneous Medicine and Surgery” Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
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January 1996 in “Gynecological endocrinology” This article describes a case of severe hyperandrogenism in a 35-year-old woman where high-resolution imaging ruled out tumors, and treatment with cyproterone acetate normalized testosterone levels.
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January 1995 in “Journal of Investigative Dermatology” RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.
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January 1989 in “Handbook of experimental pharmacology” This article reviews the use of anti-androgens for dermatological conditions linked to androgen involvement and reports encouraging clinical experiences in females, with use in males limited to specific conditions due to toxicity concerns.
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January 1979 in “International Journal of Dermatology” This article reviews the use of anti-androgens, particularly cyproterone acetate, for managing hirsutism, but does not provide new clinical results.
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February 1971 in “JAMA” This study found that hair growth was maintained in alopecic sites using scalp autografts with triamcinolone acetonide, but homografts were typically rejected.
May 2026 in “Cell Reports Medicine” This study develops FR-1, a topical small molecule, which reduces scarring and avoids skin atrophy in a murine wound model, showing potential for treating fibrosis without the side effects of current therapies.
March 2025 in “Pakistan Journal of Health Sciences” In this study, patients with Alopecia Areata showed significant clinical improvement after intralesional steroid treatment, as trichoscopic features like black dots and exclamation mark hairs decreased, while short vellus and circle hairs increased, highlighting Trichoscopy's utility in monitoring treatment response.
November 2023 in “Aktualʹnì problemi sučasnoï medicini” This article provides a review of alopecia areata, highlighting the development of diagnostic and therapeutic algorithms that consider factors such as age, disease severity, and quality of life, but it reports no new clinical findings.
February 2023 in “Journal of clinical medicine research” This study found that zinc acetate hydrate may improve fatigue and hair loss symptoms in post-COVID-19 patients.
Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.
January 2014 in “Side effects of drugs annual” This review discusses the 2011 publications on the side effects of sex hormones and related compounds, without reporting new clinical results.
January 1989 in “Handbook of experimental pharmacology” This review discusses the impact of drugs on human hair growth, highlighting its psychological importance and noting that most contributions are from clinical perspectives, with some input from biochemists and physiologists.
September 1987 in “International Journal of Dermatology” Cimetidine is not a first-choice treatment for female hair loss, and there's no consistently successful treatment for this condition in men or normal hormone level women.
September 1987 in “International Journal of Dermatology” This article is a reply to Dr. Greenwald and does not provide new clinical results.
August 2026 in “Medicina Clínica Práctica” In this case report, a patient with progressive hair loss linked to hair-pulling during emotional stress showed marked improvement in hair density after treatment with oral N-acetylcysteine and topical minoxidil, along with cessation of the hair-pulling behavior.
August 2026 in “International Journal of Research in Dermatology” This case study reports co-localized vitiligo and alopecia areata on the scalp of a 33-year-old Indian male, with marked improvement following intralesional corticosteroid treatment, suggesting a shared autoimmune pathogenesis.
August 2026 in “Experimental Dermatology” This study found that a high-fat diet exacerbates hair loss in female mice by increasing oxidative stress and androgen signaling in the skin, and that treatments with antioxidants or antiandrogens may help mitigate this effect.
July 2026 in “Journal of Cutaneous and Aesthetic Surgery” This study found that intralesional Vitamin D3 injections were comparable in efficacy to intralesional triamcinolone for patchy alopecia areata, with a non-significant trend towards better outcomes and fewer local adverse effects.
July 2026 in “Journal of Ovarian Research” In this review, researchers provided a comprehensive analysis of anti-androgen therapies for polyendocrine metabolic ovarian syndrome (PMOS/PCOS), examining their efficacy and safety while proposing a phenotype-guided management framework and highlighting research gaps, such as long-term cardiovascular safety and predictive biomarkers.
July 2026 in “Clinical Cosmetic and Investigational Dermatology” In this case report, a 9-year-old boy with Sjogren-Larsson syndrome was also diagnosed with central precocious puberty, showing genetic mutations and increased hormone levels; he was treated with triptorelin acetate for CPP but experienced growth delay during follow-up.
June 2026 in “Quality in Sport” This study reviewed the current understanding of congenital adrenal hyperplasia from 21-hydroxylase deficiency, highlighting the impact of universal newborn screening in reducing mortality and discussing ongoing treatment challenges and future therapeutic prospects.
May 2026 in “Journal of Asia Pacific Aesthetic Sciences” This case report highlights significant hair regrowth in a Malaysian woman with localized alopecia areata after intralesional triamcinolone acetonide treatment at a concentration of 5 mg/mL.
March 2026 in “Animal Models and Experimental Medicine” In a dermal Gorab knockout mouse model, this study found that Gorab mutations increase P53 protein accumulation and disrupt extracellular matrix expression, contributing to accelerated skin aging and suggesting a pathway involving epigenetic regulation.
February 2026 in “Advanced Science” This study found that targeting the p300/androgen receptor axis effectively reduced AR activation and ovarian fibrosis in mouse models of polycystic ovary syndrome, suggesting a potential therapeutic approach.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated the effect of statins on alopecia areata improvement in a large retrospective cohort and found that statins do not independently predict improvement in this hair disorder. Age and intralesional triamcinolone acetonide injections were identified as better predictors.
January 2026 in “Ciencia Latina Revista Científica Multidisciplinar” In this case study, a 14-year-old boy with treatment-resistant diffuse alopecia areata achieved complete hair regrowth following three monthly sessions of microneedling combined with injections of triamcinolone, dutasteride, and synthetic exosomes, suggesting that exosome-based therapy could be a promising alternative for managing refractory autoimmune alopecia.
January 2026 in “BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY” In this randomized controlled trial, both Botulinum Toxin-A and Triamcinolone Acetonide showed substantial effectiveness in treating patchy Alopecia Areata, but Botulinum Toxin-A avoided complications while Triamcinolone led to skin atrophy in 16.7% of patients.
This case study reports a rare instance of both alopecia areata and fixed drug eruption occurring in the same area on a 40-year-old man's beard, triggered by oral paracetamol, highlighting potential shared pathogenic pathways and the isotopic phenomenon.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review reports that anti-androgens, often combined with contraception, are supported for managing PCOS symptoms related to high androgen levels, but uncertainties remain about long-term safety and metabolic effects, indicating a need for future research on various treatment approaches.