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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.

Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.

Some medicinal plants can help heal wounds and may lead to new treatments.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Women with PCOS have lower quality of life, especially in mental health and energy, and managing weight can help improve it.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Low-level laser therapy, now called photobiomodulation, is recognized for its broad medical applications and scientific backing.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.

Estrogen therapy can reduce skin aging but has cancer risks.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.