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    Did you mean Gamma-Linolenic Acid?
    Glossary Gamma-Linolenic Acid

    omega-6 fatty acid found in certain plant oils

    Gamma-Linolenic Acid (GLA) is an omega-6 fatty acid found in various plant oils, such as evening primrose oil and borage oil. It plays a crucial role in maintaining healthy skin and hair by reducing inflammation and supporting cell structure. GLA is often used in supplements to manage conditions like eczema, psoriasis, and hair loss due to its anti-inflammatory properties.

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    1. Abnormal essential fatty acid composition of tissue lipids in genetically diabetic mice is partially corrected by dietary linoleic and γ-linolenic acids British journal of nutrition · 1985 · 20 citations
    2. Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction European Journal of Pharmaceutics and Biopharmaceutics · 2012 · 21 citations
    3. The extract of Thujae occidentalis semen inhibited 5α-reductase and androchronogenetic alopecia of B6CBAF1/j hybrid mouse Journal of dermatological science · 2003 · 47 citations
    4. Acne 2019 · 4 citations
    5. <i>In Vivo</i> Hair Growth-Promoting Effect of Rice Bran Extract Prepared by Supercritical Carbon Dioxide Fluid Biological & Pharmaceutical Bulletin · 2013 · 32 citations
    6. Deciphering the Skin Anti-Aging and Hair Growth Promoting Mechanisms of Opophytum forskahlii Seed Oil via Network Pharmacology International Journal of Molecular Sciences · 2025
    7. TGFβ signaling regulates lipogenesis in human sebaceous glands cells BMC Dermatology · 2013 · 44 citations
    8. Fatty acids and related lipid mediators in the regulation of cutaneous inflammation Biochemical Society Transactions · 2018 · 28 citations
    9. The Role of Linoleic Acid in Skin and Hair Health: A Review International Journal of Molecular Sciences · 2024
    10. An Uncontrolled Case Series Using a Botanically Derived, β-Cyclodextrin Inclusion Complex in Two Androgenetic Alopecia-Affected Male Subjects Cosmetics · 2020 · 2 citations
    11. 5α-Reductase type 1 inhibition of Oryza sativa bran extract prepared by supercritical carbon dioxide fluid Journal of Supercritical Fluids · 2011 · 22 citations
    12. Physiological and pharmacological features of the non-saponin components in Korean Red Ginseng Journal of Ginseng Research · 2020 · 67 citations
    13. Studies of the modulation of MHC antigen and cell adhesion molecule expression on human dermal papilla cells Journal of dermatological science · 1994
    14. Effects of Bioactive Composition in Oryza sativa L. cv. KDML105 Bran Extract on Gene Expression Related to Hair Cycle in Human Hair Follicle Dermal Papilla Cells Agronomy · 2023 · 3 citations
    15. Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata Frontiers in Pharmacology · 2025
    16. The Chemical and Pharmacological Research Progress on a Kind of Chinese Herbal Medicine, Fructus Malvae Molecules · 2022 · 1 citations
    17. Adipocytes in Skin Health and Disease Cold Spring Harbor Perspectives in Medicine · 2014 · 77 citations
    18. 870 Y27632 promotes proliferation via EGFR signaling in a newly isolated and characterized human primary sebocyte cell line Journal of Investigative Dermatology · 2019
    19. Physico-Chemical Characteristics of Rosa canina L. Seeds and Determining Their Potential Use Applied Sciences · 2024 · 4 citations
    20. Essential Fatty Acid Deficiency (EFAD) in a Patient with Vascular Ehlers Danlos Syndrome (EDS-4) (P12-053-19) Current developments in nutrition · 2019 · 1 citations
    21. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism bioRxiv (Cold Spring Harbor Laboratory) · 2026
    22. Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures PLoS ONE · 2013 · 60 citations
    23. Azelaic Acid: Mechanisms of Action and Clinical Applications Clinical Cosmetic and Investigational Dermatology · 2024 · 34 citations
    24. Supercritical CO<sub>2</sub> Extraction of Rice Bran Oil –the Technology, Manufacture, and Applications Journal of Oleo Science · 2017 · 23 citations
    25. Micronutrients for Hair and Nails Springer eBooks · 2010 · 1 citations
    26. Nutritional factors and hair loss Clinical and Experimental Dermatology · 2002 · 239 citations
    27. TREATMENT PEARLS FROM EUROPE Dermatologic Clinics · 1998 · 2 citations
    28. Nutritional Management of Menopausal Women Springer eBooks · 2017
    29. Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome European journal of endocrinology · 2009 · 200 citations
    30. Vpliv prehrane na pojavnost aken Repository of the University of Primorsk (University of Primorska) · 2023