Search
for

    Did you mean Dihydrotestosterone?
    Glossary Dihydrotestosterone

    potent androgen hormone derived from testosterone

    Dihydrotestosterone (DHT) is a potent androgen hormone derived from testosterone through the action of the enzyme 5-alpha-reductase. It plays a crucial role in the development of male characteristics and is also implicated in conditions like androgenic alopecia (male pattern baldness) and benign prostatic hyperplasia.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. 5 Dihydrotestosterone metabolism Clinics in endocrinology and metabolism · 1986 · 22 citations
    2. An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 5-alpha-dihydrotestosterone in human serum and plasma Clinical Chemistry and Laboratory Medicine (CCLM) · 2026
    3. DIHYDROTESTOSTERONE AND THE PROSTATE: THE SCIENTIFIC RATIONALE FOR 5α-REDUCTASE INHIBITORS IN THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA 2004 · 235 citations
    4. Dihydrotestosterone and the Concept of 5α–Reductase Inhibition in Human Benign Prostatic Hyperplasia European Urology · 2000 · 184 citations
    5. Dihydrotestosterone and 5α-Reductase Humana Press eBooks · 2003
    6. Preponderance of serum and intra-hepatic 5α-dihydrotestosterone in males with hepatocellular carcinoma despite low circulating androgen levels Journal of hepatology · 1986 · 8 citations
    7. The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness. The Journal of Clinical Endocrinology and Metabolism · 1994 · 59 citations
    8. Comparative Efficacy of Oral and Topical 5-Alpha Reductase Inhibitors in Reducing Dihydrotestosterone levels across Men with Androgenetic Alopecia: A Network Meta-Analysis incorporating Post-Hoc Analyses of Randomized Clinical Trial Data Open Science Framework · 2026
    9. Analysis of the microRNA expression profile of normal human dermal papilla cells treated with 5α-dihydrotestosterone Molecular Medicine Reports · 2012 · 22 citations
    10. Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells Skin Pharmacology and Physiology · 2006 · 58 citations
    11. Sexual dimorphism of growth plate prehypertrophic and hypertrophic chondrocytes in response to testosterone requires metabolism to dihydrotestosterone (DHT) by steroid 5‐alpha reductase type 1 Journal of Cellular Biochemistry · 2005 · 27 citations
    12. Effect of MK-386, a novel inhibitor of type 1 5 alpha-reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men. The Journal of Clinical Endocrinology and Metabolism · 1996 · 6 citations
    13. Longitudinal clinical course in patients with 5α-reductase type 2 deficiency treated with testosterone and dihydrotestosterone during infancy and puberty Endocrine journal · 2022
    14. Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor 2004 · 408 citations
    15. Testosterone Reduces Knee Passive Range of Motion and Expression of Relaxin Receptor Isoforms via 5α-Dihydrotestosterone and Androgen Receptor Binding International Journal of Molecular Sciences · 2014 · 23 citations
    16. The circulating dihydrotestosterone/testosterone ratio is increased by gut microbial 5α-reductase activity in females EBioMedicine · 2025 · 1 citations
    17. Terminalia chebula retz. Fruit Extract Promotes Murine Hair Growth by Suppressing 5α-Reductase and Accelerating the Degradation of Dihydrotestosterone Biomedicines · 2025
    18. The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness The Journal of Clinical Endocrinology and Metabolism · 1994 · 61 citations
    19. Effect of MK-386, a novel inhibitor of type 1 5 alpha-reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men The Journal of Clinical Endocrinology and Metabolism · 1996 · 7 citations
    20. The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications The Prostate · 1986 · 57 citations
    21. Clinical biochemistry of dihydrotestosterone Annals of Clinical Biochemistry · 2013 · 50 citations
    22. Effects of Androgen Treatment on Growth in Patients with 5-α-Reductase Type 2 Deficiency Journal of personalized medicine · 2023
    23. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011 · 218 citations
    24. Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production JAMA · 2012 · 124 citations
    25. 5alpha-reductase: history and clinical importance. PubMed · 2004 · 62 citations
    26. 5-Alpha reductase deficiency Current Opinion in Endocrinology, Diabetes and Obesity · 2014 · 38 citations
    27. Dutasteride: a review of current data on a novel dual inhibitor of 5alpha reductase. PubMed · 2005 · 38 citations
    28. Biosynthesis of Dihydrotestosterone by a Pathway that Does Not Require Testosterone as an Intermediate in the SZ95 Sebaceous Gland Cell Line Journal of Investigative Dermatology · 2009 · 36 citations
    29. Long-term Oral Administration of 5α-reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats Urology · 2013 · 34 citations
    30. Morphology of the testis and the epididymis in rats with dihydrotestosterone (DHT) deficiency. PubMed · 2004 · 34 citations