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    Research 31–60 of 1000+

    1. Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice Journal of Ethnopharmacology · 2015 · 25 citations
    2. Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors Bioorganic & Medicinal Chemistry · 2015 · 17 citations
    3. 5alpha-reductase inhibitors - a new hope in dermatology? International Journal of Dermatology · 1997 · 15 citations
    4. Steroid 5α-reductase 2 deficiency leads to reduced dominance-related and impulse-control behaviors Psychoneuroendocrinology · 2018 · 14 citations
    5. Docking and Molecular Dynamics Identify Leads against 5 Alpha Reductase 2 for Benign Prostate Hyperplasia Treatment Journal of Chemistry · 2023 · 10 citations
    6. Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment F1000Research · 2021 · 8 citations
    7. An update on the use of 5alpha-reductase inhibitors Drugs of today · 2004 · 7 citations
    8. Pharmacodynamic modeling of finasteride, a 5 alpha-reductase inhibitor. PubMed · 1995 · 7 citations
    9. Long-Term Experience With 5-alpha-Reductase Inhibitors. PubMed · 2003 · 6 citations
    10. The novel drug CS-891 inhibits 5alpha-reductase activity in freshly isolated dermal papilla of human hair follicles. PubMed · 2000 · 3 citations
    11. Purple corn extract improves benign prostatic hyperplasia by inhibiting 5 alpha-reductase type 2 and inflammation in testosterone propionate-induced rats Frontiers in Pharmacology · 2025 · 2 citations
    12. 5 alpha-reductase inhibition by a new synthetic steroid (PM-9) in cultures of Penicillium crustosum. PubMed · 2002 · 1 citations
    13. Natural Product-Inspired Bis(trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, <i>In Vitro</i>, and <i>In Silico</i> Studies ACS Omega · 2025
    14. 5 Alpha - Reductase and Metabolic Syndrome in PCOS Patients International Journal of Science and Research (IJSR) · 2021
    15. A Review on Finasteride: A 5-Alpha Reductase Inhibitors, its Mechanism, Facts and Benefits Journal of Drug Delivery and Therapeutics · 2019
    16. The enzyme and inhibitors of 4-ene-3-oxosteroid 5α-oxidoreductase Steroids · 1995 · 64 citations
    17. The biochemical and phenotypic characterization of females homozygous for 5 alpha-reductase-2 deficiency. The Journal of Clinical Endocrinology & Metabolism · 1995 · 54 citations
    18. Cloning, computational analysis and expression profiling of steroid 5 alpha-reductase 1 (SRD5A1) gene during reproductive phases and ovatide stimulation in endangered catfish, Clarias magur Scientific reports · 2023
    19. The 5α-Recluctase System and Its Inhibitors Dermatology · 1996 · 124 citations
    20. Structure of human type II 5 alpha-reductase gene. Endocrinology · 1992 · 124 citations
    21. 9 Role of 5α-reductase in health and disease Baillière's clinical endocrinology and metabolism · 1994 · 101 citations
    22. Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase Journal of Medicinal Chemistry · 1993 · 89 citations
    23. 5-Alpha Reductase Inhibitors and Erectile Dysfunction: The Connection The Journal of Sexual Medicine · 2008 · 78 citations
    24. Comparison of Finasteride (Proscar®) and Serenoa repens (Permixon®) in the Inhibition of 5-Alpha Reductase in Healthy Male Volunteers European Urology · 1994 · 73 citations
    25. Finasteride: A slow-binding 5.alpha.-reductase inhibitor Biochemistry · 1993 · 70 citations
    26. Dihydrotestosterone Stimulates 5a-Reductase Activity in Pubic Skin Fibroblasts* 1983 · 57 citations
    27. LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1. Proceedings of the National Academy of Sciences of the United States of America · 1993 · 53 citations
    28. Nipple Differentiation in Fetal Male Rats Treated with an Inhibitor of the Enzyme 5<i>α</i>-Reductase: Definition of a Selective Role for Dihydrotestosterone* Endocrinology · 1986 · 53 citations
    29. Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary–adrenal axis response to restraint stress in adult male rats Brain Research · 2013 · 51 citations
    30. The effect of spironolactone on genital skin 5α-reductase activity 1985 · 50 citations