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Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Safflower extract in nanostructured carriers was more effective than minoxidil for hair growth without irritating skin.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

Finasteride helps reduce heart enlargement in heart failure patients.

Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.

Topical therapies show promise for hair loss and acne treatment with minimal side effects.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Four-amino acid part makes enzyme sensitive to finasteride.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Some herbs show promise as antiandrogenic agents.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.