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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Apoptosis is essential for human skin development and forming a functional epidermis.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Finasteride may cause long-lasting sexual side effects.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

New treatments for male hypogonadism are effective and should be personalized.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Neurosteroids show promise for treating epilepsy and more research is needed.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.