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New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

A COVID-19 patient had unusual nail discoloration and nail separation possibly due to the virus's effects on small blood vessels.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

A new gene mutation causes insulin resistance in a girl and her mother.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Researchers developed a method to create artificial hair follicles that may help with hair loss treatment and research.

Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.

Copper treatments increase copper in all tissues, but brindled female mice accumulate much more copper in their kidneys without clinical effects, unlike brindled male mice where brain copper deficiency is clinically significant.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

Low-dose finasteride effectively reduces hirsutism without serious side-effects.

Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.

Syphilitic alopecia, linked to syphilis and high-risk sexual behavior, improves with penicillin treatment.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Finasteride may cause kidney damage.

The study created a new method to test drugs that affect hormone processing in skin.