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Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

The document concludes that accurate diagnosis and management of PCOS are crucial due to its associated health risks.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Adrenal disorders can cause lasting brain and behavior issues in children.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Certain drugs that block specific enzymes can help treat prostate diseases.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Blood AMH levels are higher in women with PCOS than in those with other similar conditions.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.