49 citations
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March 2018 in “Toxicological sciences” In this study, male rats exposed in utero to low-dose chemical mixtures had permanent reproductive tract alterations, suggesting additive effects even at doses below individual adverse levels.
61 citations
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June 2016 in “Clinical Medicine” This review discusses the relationship between obesity, insulin resistance, and polycystic ovary syndrome and highlights the potential benefits of weight loss for managing PCOS symptoms, but reports no new clinical results.
44 citations
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June 1967 in “The journal of nutrition/The Journal of nutrition” This study found that essential fatty acid deficiency in rabbits leads to significant degeneration of gonadal tissue, possibly due to impaired anterior pituitary gland function.
January 1987 in “Toxicological sciences” In this study, SMR-2 and SMR-6, retinoid analogs, were found to be approximately 100 times more toxic than retinoic acid in male mice, primarily affecting skin, immune, and reproductive systems.
June 2021 in “Archives of Advances in Biosciences” This study suggests that finasteride at doses of 5 mg/kg BW or higher may adversely affect spermatogenesis and male fertility in NMRI mice.