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      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

    Research

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      community DHT Isn't (Directly) Important

      in Research/Science  100 upvotes 2 weeks ago
      Finasteride's potential side effects, especially sexual dysfunction, are discussed, with emphasis on hormonal balance between testosterone and estradiol. Users share experiences with finasteride, minoxidil, and dutasteride, highlighting the variability in side effects and the influence of mindset and lifestyle.

      community Methods Of Staying Safe On Ru58841 - My 2 Cents

      in Research/Science  12 upvotes 1 month ago
      RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 5 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Wtf have we been doing for the last 30 years

      in Treatment  548 upvotes 2 months ago
      Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.