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research Determination of Protonation State in Molecular Salt of Minoxidil and 2,4-Dihydroxybenzoic Acid Through a Combined Experimental and Theoretical Study: Influence of Proton Transfer on Biological Activities

12 citations, September 2021 in “Journal of molecular structure”

The MXD/24HA salt is more effective for hair growth than raw MXD.

Chemical Mechanism of the Covalent Modification of 5-Alpha-Reductases by Finasteride as Probed by Secondary Tritium Isotope Effects

research Chemical Mechanism of the Covalent Modification of 5-Alpha-Reductases by Finasteride as Probed by Secondary Tritium Isotope Effects

12 citations, March 1995 in “Journal of the American Chemical Society”

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders

72 citations, January 2011 in “Current Pharmaceutical Design”

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

research Voltammetric Reduction of Finasteride at Mercury Electrode and Its Determination in Tablets

21 citations, May 2008 in “Talanta”

New, cheaper method measures finasteride in tablets accurately and quickly.

Surface Modification and Endothelialization of Biomaterials as Potential Scaffolds for Vascular Tissue Engineering Applications

research Surface Modification and Endothelialization of Biomaterials as Potential Scaffolds for Vascular Tissue Engineering Applications

421 citations, January 2015 in “Chemical Society Reviews”

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

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Community Join

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community 1.5 years on fin and min (24 yo). Start early guys, it’s worth it.

in Progress Pictures 1167 upvotes 1 year ago

The conclusion of the conversation is that the user "CheckHopeful" has seen significant improvement in their hair loss after using finasteride and minoxidil for 1.5 years. Some users discuss side effects and suggest adjusting the dosage or trying topical finasteride or RU58841.

community Sanguisorba Officinalis Root Extract, and other FGF-5 inhibitors?

in Question 4 upvotes 7 years ago

The conversation discusses the potential of Sanguisorba Officinalis Root Extract as a treatment for hair loss by inhibiting FGF-5. The user also mentions the product évolis, which is based on this extract but is only available in the US and Australia.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 8 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.