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GlossaryPro-inflammatory cytokines

signaling molecules that trigger inflammation in the body

Pro-inflammatory cytokines are signaling molecules released by immune cells that promote inflammation in the body. They play a crucial role in the immune response by helping to fight off infections and heal injuries, but excessive or chronic production can lead to inflammatory diseases such as rheumatoid arthritis, psoriasis, and alopecia areata. Examples include tumor necrosis factor-alpha (TNF-α), interleukin-1 (IL-1), and interleukin-6 (IL-6).

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Treatment with Light-Emitting Diodes of Wavelength 863 nm Delays DMBA/TPA-Induced Skin Tumor Formation and Decreases Proinflammatory Cytokine Levels in ICR Mice

research Treatment with Light-Emitting Diodes of Wavelength 863 nm Delays DMBA/TPA-Induced Skin Tumor Formation and Decreases Proinflammatory Cytokine Levels in ICR Mice

2 citations, February 2022 in “BioMed Research International”

LED light therapy at 863 nm wavelength can slow down skin tumor growth and reduce inflammation in mice.

research Discovery Of A Novel And Highly Selective JAK3 Inhibitor As A Potent Hair Growth Promoter

April 2024 in “Journal of translational medicine”

MJ04, a new compound, effectively promotes hair growth and is a potential topical treatment for hair loss.

research Beneficial Effects of Finasteride on Hepatic and Pulmonary Immune Response After Trauma Hemorrhage in Mice

1 citations, July 2015 in “Cytokine”

Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.

research Research Gaps in Medical Treatment of Transgender and Nonbinary People

19 citations, February 2021 in “Journal of Clinical Investigation”

More research is needed on the health effects of hormone therapy for transgender and nonbinary people.

research Inheritance-Specific Dysregulation of Th1 and Th17-Associated Cytokines in Alopecia Areata

1 citations, August 2023 in “Biomolecules”

Certain immune-related proteins are higher in people with alopecia and their healthy relatives, hinting at a genetic link.

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community dht becoming active since the scalp is tight en cause inflammation

in Research/Science 6 upvotes 2 years ago

User discusses tight scalp causing hair loss and suggests treatments like scalp massages, PRP, saw palmetto, and eucapil. They share their experience with saw palmetto and eucapil and consider adding PRP and scalp massages for better results.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 122 upvotes 6 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 7 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community Unofficial Dermapen/Roller Guide

in Treatment 253 upvotes 5 years ago

Treatments for hair loss, including microneedling (dermarolling and dermapen) and the use of minoxidil, finasteride, and RU58841. It provides detailed information about cost and usage of the various treatments, as well as potential side effects.

community Keratin microspheres - breakthrough

in Research/Science 13 upvotes 8 months ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

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