January 2020 in “Current trends in diagnosis & treatment”
This review discusses the off-label use of drugs and emphasizes the need for standardized guidelines due to varying international regulations and safety concerns, but reports no new clinical results.
Drug companies were interested in advertising directly to consumers to make back their money, but most didn't think it would help and were concerned about negative effects.
8 citations
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August 2018 in “International Journal of Dermatology”
This study discusses the prevalence and ethical considerations of off-label drug use in dermatology, emphasizing differing perspectives on informed consent between patients and physicians.
OP is concerned about hairline recession and was advised by dermatologists to use Minoxidil on the hairline, despite doubts about its effectiveness there. OP is unsure about not being prescribed Finasteride and is considering whether to seek it independently.
The conversation discusses concerns about using a high concentration of 1% topical finasteride for hairline balding, with some users suggesting starting with a lower dose. It also mentions the use of GHK-CU peptide and the importance of considering the formulation to avoid excessive absorption.
A woman with advanced AGA is seeking ways to obtain Dutasteride without a prescription due to difficulties with traditional methods and concerns about birth defects, despite being celibate and on birth control. Users suggest various online sources and alternatives like topical anti-androgens, while cautioning about potential risks and side effects.
A dermatologist prescribed 0.5mg dutasteride every two days and 5mg Minoxidil daily for hair loss, suggesting dutasteride mesotherapy as an alternative. The discussion questions the effectiveness and cost of mesotherapy compared to oral treatments, with concerns about side effects and the dermatologist's approach.
The user switched from prescribed topical minoxidil and finasteride to stronger grey market alternatives, hoping for better hair growth but experiencing shedding. Concerns were raised about the legitimacy and safety of grey market products, with suggestions to use prescribed medications instead.
Is it dangerous to buy dutasteride without a prescription? Dutasteride is a prescription medicine, and its US label warns about a PSA drop, a higher rate of high-grade prostate cancer in one trial, sexual and breast side effects (the sexual ones may persist after stopping, with dutasteride's role unknown), depressed mood and a new UK class warning about depression and suicidal thoughts, risks in pregnancy and a 6-month blood-donation deferral. Buying from unregulated online sellers adds the risk of counterfeit or contaminated products.
Do I need a prescription to take cyproterone?Cyproterone acetate is a prescription-only medicine in every country that licenses it, and it has no FDA approval in the United States — regulators require a prescriber because the drug needs hormonal and liver monitoring and carries a dose-related meningioma risk flagged by the EMA in 2020.