 
    Not having the gene PLAAT3 leads to fat loss, high insulin resistance, and abnormal fat levels in the blood due to a disruption in fat cell development and function.  
      150 citations
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  October 2010   in “The American Journal of Pathology”
           150 citations
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  October 2010   in “The American Journal of Pathology”    The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.  
      87 citations
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  March 2014   in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids”
           87 citations
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  March 2014   in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids”    Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.  
      102 citations
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  July 2007   in “Genes & Development”
           102 citations
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  July 2007   in “Genes & Development”    A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.  
      50 citations
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  September 2011   in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids”
           50 citations
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  September 2011   in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids”    Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.