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Research

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research Evaluating the psychosocial impact of gender‐affirming dermatology treatments: A systematic review

January 2024 in “JEADV clinical practice”

This study reviewed research on the psychosocial effects of gender-affirming dermatology treatments in transgender populations, finding mostly positive associations but noting significant limitations and the need for more comprehensive studies to clearly understand these effects.

research Sleep disturbances in women with polycystic ovary syndrome

19 citations , June 2016 in “Gynecological Endocrinology”

This study reported that women with Polycystic Ovary Syndrome have higher rates of clinically significant insomnia and excessive daytime sleepiness than women without the condition, highlighting the need for sleep disorder screening in this population.

research CD8-positive Lymphocytes in Graft-Versus-Host Disease of Humanized NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ Mice

7 citations , February 2015 in “Journal of comparative pathology”

This study observed that NSG-hu-BLT mice developed graft-versus-host disease characterized by CD8+ T lymphocyte-related cell death in the skin and liver, which may affect their utility in other research areas.

research An Uncontrolled Case Series Using a Botanically Derived, β-Cyclodextrin Inclusion Complex in Two Androgenetic Alopecia-Affected Male Subjects

2 citations , August 2020 in “Cosmetics”

This study reported unexpected positive results in two males with androgenetic alopecia using a cyclodextrin-enabled, natural-based formula over 270 days, showing marked hair thickening and reduced scalp hair loss.

research 1373 Specific in vivo ablation of Lrig1-positive follicular stem cells results in sebaceous gland loss in mice

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

The authors concluded that Lrig1-positive stem cells are essential for sebaceous gland formation in mice, as their ablation led to temporary sebaceous gland disappearance without affecting hair growth.

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Community Join

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community Finasteride Mono-Therapy 6 month check in

in Progress Pictures 6 upvotes 1 year ago

The user reports positive results from using finasteride for six months, noticing hair regrowth despite ongoing shedding and dry scalp issues. They suspect hard water and a possible vitamin D deficiency may also affect their hair condition.

community Minoxidil inhibits lysyl hydroxylase which is needed to produce collagen. If I take 2,5...5 mg of minoxidil every day can I cause my skin to age prematurely?

32 upvotes 1 year ago

Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.

community M22. Does sebderm decrease effects of min and fin or I am simply fin and min nonresponder?

in Update 1 upvotes 1 year ago

The user has been using minoxidil and finasteride for hair loss without positive results and switched to dutasteride 1.5 months ago. They suspect seborrheic dermatitis might be affecting the effectiveness of these treatments.

community Im excited on things to come. Gonna add dermaroller to this. Oral fin 5x/wk. Topical min 2x/day.

in Progress Pictures 10 upvotes 1 year ago

A user shared their hair loss treatment routine, which includes oral finasteride 5 times a week and topical minoxidil twice a day, and plans to add microneedling. They reported positive results, with reduced bald spots and no side effects affecting libido or physical strength.

community Any positive experiences from homemade low dose (0.01%) topical fin? (Male, Age 18)

in Basic Questions 87 upvotes 5 months ago

An 18-year-old male experienced positive results with oral finasteride but stopped due to side effects and is now trying homemade low-dose (0.01%) topical finasteride mixed with liquid minoxidil to manage hair loss. He seeks feedback on the effectiveness of this DIY topical treatment.

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Learn

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learn Hair Transplant

What is the success rate of hair transplants? Clinics report high graft survival, but there is no independent overall success rate and results vary.

learn Melatonin

Sleep hormone. One small trial in 40 women and some uncontrolled studies suggest topical melatonin may affect the hair cycle, but evidence is weak.

learn Pyrilutamide

Pyrilutamide (KX-826) is an investigational topical antiandrogen. It is not approved anywhere, and its trial results, including a failed 2023 Phase III and a positive 2026 one, are sponsor-reported and not peer-reviewed.

learn Clascoterone

An androgen-receptor blocker approved only for acne (Winlevi 1% cream). A scalp solution is still investigational for hair loss; its sponsor reports positive Phase III results in men, not yet peer-reviewed.

learn HMI-115

Investigational antibody that blocks the prolactin receptor; tested in pattern hair loss, not approved, and no hair-loss results published.

learn Platelet-Rich Plasma

a concentrate of your own blood platelets injected into the scalp; used off-label for hair loss, with mixed evidence

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Clinics

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