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    Did you mean Polygenic Risk Score?
    Glossary Polygenic Risk Score

    numerical estimate of genetic predisposition based on multiple variants

    A Polygenic Risk Score (PRS) is a numerical value that estimates an individual's genetic predisposition to a particular trait or disease, based on the cumulative effect of multiple genetic variants. By analyzing data from genome-wide association studies (GWAS), researchers can calculate a PRS to predict the likelihood of conditions such as alopecia, heart disease, or diabetes, providing valuable insights for personalized medicine and preventive healthcare.

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    1. 129 Utilizing Polygenic score in predicting the disease activity and arthritis in psoriasis patients Journal of Investigative Dermatology · 2024
    2. Polygenic risk score predicting susceptibility and outcome of benign prostatic hyperplasia in the Han Chinese Human Genomics · 2024 · 1 citations
    3. Polygenic risk score predicting susceptibility and outcome of benign prostatic hyperplasia in the Han Chinese Research Square (Research Square) · 2023
    4. Evidence for a polygenic contribution to androgenetic alopecia British Journal of Dermatology · 2013 · 26 citations
    5. Predicting hair cortisol levels with hair pigmentation genes: a possible hair pigmentation bias Scientific Reports · 2017 · 23 citations
    6. Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies Frontiers in Pharmacology · 2026
    7. Multi-ancestry tandem repeat association study of hair colour using exome-wide sequencing bioRxiv (Cold Spring Harbor Laboratory) · 2024
    8. Reconsidering the Polycystic Ovary Syndrome (PCOS) Biomedicines · 2022 · 41 citations
    9. Analysis of 72,469 UK Biobank exomes links rare variants to male-pattern hair loss Nature Communications · 2023
    10. Pediatric Features of Genetic Predisposition to Polycystic Ovary Syndrome ˜The œJournal of clinical endocrinology and metabolism · 2023
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