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    Did you mean Polygenic Risk Score?
    Glossary Polygenic Risk Score

    numerical estimate of genetic predisposition based on multiple variants

    A Polygenic Risk Score (PRS) is a numerical value that estimates an individual's genetic predisposition to a particular trait or disease, based on the cumulative effect of multiple genetic variants. By analyzing data from genome-wide association studies (GWAS), researchers can calculate a PRS to predict the likelihood of conditions such as alopecia, heart disease, or diabetes, providing valuable insights for personalized medicine and preventive healthcare.

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    1. 129 Utilizing Polygenic score in predicting the disease activity and arthritis in psoriasis patients Journal of Investigative Dermatology · 2024
    2. Polygenic risk score predicting susceptibility and outcome of benign prostatic hyperplasia in the Han Chinese Human Genomics · 2024 · 1 citations
    3. Polygenic risk score predicting susceptibility and outcome of benign prostatic hyperplasia in the Han Chinese Research Square (Research Square) · 2023
    4. Evidence for a polygenic contribution to androgenetic alopecia British Journal of Dermatology · 2013 · 26 citations
    5. Predicting hair cortisol levels with hair pigmentation genes: a possible hair pigmentation bias Scientific Reports · 2017 · 23 citations
    6. Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies Frontiers in Pharmacology · 2026
    7. Multi-ancestry tandem repeat association study of hair colour using exome-wide sequencing bioRxiv (Cold Spring Harbor Laboratory) · 2024
    8. Reconsidering the Polycystic Ovary Syndrome (PCOS) Biomedicines · 2022 · 41 citations
    9. Analysis of 72,469 UK Biobank exomes links rare variants to male-pattern hair loss Nature Communications · 2023
    10. Pediatric Features of Genetic Predisposition to Polycystic Ovary Syndrome ˜The œJournal of clinical endocrinology and metabolism · 2023
    11. What Is the Male Polycystic Ovary Syndrome Phenotype? 2021
    12. Systematic investigation of a potential epidemiological and genetic association between male androgenetic alopecia and COVID‐19 Skin health and disease · 2021 · 2 citations
    13. A Genetically Defined Male Counterpart of Polycystic Ovary Syndrome: Evidence for Ovarian-Independent Pathogenesis Journal of the Endocrine Society · 2021 · 2 citations
    14. Dermatological diseases from a genetic perspective Medizinische Genetik · 2023
    15. Do Alopecia Areata and Hair Colour Have a Shared Genetic Component? Experimental Dermatology · 2026
    16. Comparative Evaluation of Oral Baricitinib and Tofacitinib in Alopecia Areata: A Retrospective Cohort Study Based on SALT Scores Turkish Journal of Dermatology · 2025
    17. Dissection of genetic variation and evidence for pleiotropy in male pattern baldness Nature Communications · 2018 · 58 citations
    18. Comparative Efficacy and Safety of Janus Kinase Inhibitors Used in Alopecia Areata: A Systematic Review and Meta-analysis Acta dermato-venereologica · 2023 · 10 citations
    19. Effectiveness of fractional erbium–YAG laser, microneedling, platelet-rich plasma in localized stable vitiligo patients: randomized clinical trial Archives of Dermatological Research · 2024 · 5 citations
    20. Alopecia areata: An update Indian Journal of Dermatology, Venereology and Leprology · 2013 · 67 citations
    21. Experience with oral tofacitinib in 8 adolescent patients with alopecia universalis Journal of the American Academy of Dermatology · 2017 · 49 citations
    22. Bridging psychoneuroimmunology and homeopathy: Modulating the cellular and emotional cascades in refractory alopecia International Journal of Homoeopathic Sciences · 2026
    23. Alopecia areata: A review Journal of the Saudi Society of Dermatology & Dermatologic Surgery · 2013 · 29 citations
    24. Etiopathogenesis of Alopecia Areata Hair therapy & transplantation · 2014 · 2 citations
    25. Screening of Tyrosinase, Xanthine Oxidase, and α-Glucosidase Inhibitors from Polygoni Cuspidati Rhizoma et Radix by Ultrafiltration and HPLC Analysis Molecules · 2023 · 12 citations
    26. MicroRNA-mediated regulation of hair follicle regeneration: mechanisms, delivery strategies, and translational perspectives Frontiers in Cell and Developmental Biology · 2026
    27. Cross-kingdom delivery and putative gene modulation of androgen pathways by plant-derived exosome-like nanoparticles from polygoni multiflori radix promotes hair growth via miRNA cargo Pharmacological Research · 2025
    28. Clinical efficacy of silk sericin dressing with collagen for split-thickness skin graft donor site treatment 2021
    29. Preclinical Development and Phase I Study of ZSYY001, a Polymeric Micellar Paclitaxel for Advanced Solid Tumor Cancer Medicine · 2025 · 6 citations
    30. Chronic Overlapping Pain Conditions and Nociplastic Pain medRxiv (Cold Spring Harbor Laboratory) · 2023