1 citations
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April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, the researchers found that depleting natural polyamines or manipulating translation rates can enhance the stemness of hair follicle stem cells, while N1-acetylspermidine increases proliferation without affecting translation.
30 citations
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July 2010 in “Experimental Dermatology” This article reviews the role of polyamines in hair follicle growth and discusses potential therapeutic applications but provides no new clinical results.
9 citations
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April 2006 in “International Journal of Dermatology” This article reviews the potential for α-difluoromethylornithine to help control hair growth and prevent cancer, but it does not present new clinical results.
14 citations
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January 2001 in “Clinical chemistry” This article discusses the potential use of hair fibers to noninvasively measure polyamine concentrations as a marker of tumor growth, but reports no new clinical findings.
26 citations
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June 2003 in “PubMed” In this study, severe hair loss occurred in PKC epsilon transgenic mice treated with DFMO during skin tumor prevention, highlighting a link between polyamine biosynthesis, hair follicle maintenance, and metastasis suppression.