research 5-Alpha-Reductase Inhibitors and Combination Therapy 15 citations, July 2016 in “Urologic Clinics of North America” Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.
research Sexual Dysfunction Related to Drugs: A Critical Review. Part V: Alpha-Blocker and 5-ARI Drugs 15 citations, November 2015 in “Pharmacopsychiatry” α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.
research Is Tadalafil Associated With Decreased Risk of Major Adverse Cardiac Events or Venous Thromboembolism in Men With Lower Urinary Tract Symptoms? April 2022 Tadalafil may reduce the risk of major heart events and blood clots in men with urinary symptoms.
research Lower Urinary Tract Symptoms: What’s New in Medical Treatment? 22 citations, January 2018 in “European urology focus” New drugs and combination therapies are improving treatment for lower urinary tract symptoms.
research Medical Management of Benign Prostatic Hyperplasia March 2024 in “Cleveland Clinic journal of medicine” Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.