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research 60058 Change in patient-reported hair satisfaction during deuruxolitinib treatment of severe alopecia areata: Pooled data from the Phase 3 THRIVE-AA1 and THRIVE-AA2 trials

September 2025 in “Journal of the American Academy of Dermatology”

Deuruxolitinib significantly improves hair satisfaction in severe alopecia areata patients.

research TRASER: Acute phase vascular and follicular changes

4 citations , April 2014 in “Lasers in Surgery and Medicine”

This observational study reports that a TRASER device using specific wavelengths for vascular and follicular targets showed both clinical responses and histological changes, suggesting its potential as an effective vascular and hair removal tool.

research Epidermal growth factor induced apoptosis in the outer root sheath cells of anagen hair and changed the hair cycle to the catagen phase

September 2004 in “Kitasato medical journal”

This study found that a high dose of epidermal growth factor induced hair loss in sheep by causing apoptosis in anagen hair and transitioning the hair cycle to catagen.

Final Phase in the Validation of the Cross-Cultural Adaptation of the Hair-Specific Skindex-29 Questionnaire Into Spanish: Sensitivity to Change and Correlation With the 12-Item Short-Form Health Survey

research Final Phase in the Validation of the Cross-Cultural Adaptation of the Hair-Specific Skindex-29 Questionnaire Into Spanish: Sensitivity to Change and Correlation With the 12-Item Short-Form Health Survey

1 citations , November 2019 in “Actas Dermo-Sifiliográficas”

This study found that the Spanish version of the hair-specific Skindex-29 questionnaire effectively detected changes in health-related quality of life among women with female-pattern hair loss, and the scores were significantly correlated with the SF-12 survey results after treatment with a 5 alpha-reductase inhibitor.

research 192 Three-dimensional ultra-high frequency ultrasound facilitates image processing to visualize microstructural changes of hair follicles and detects distinct disease phases of alopecia areata

April 2023 in “Journal of Investigative Dermatology”

3D ultrasound can detect hair follicle changes and disease phases in alopecia areata.

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community HMI 115 Phase 1 update: Changes to clinicaltrials.gov page

25 upvotes 3 years ago

A Phase 1 update for the HMI 115 clinical trial, which involves 16 participants and is expected to end in July 2023; as well as changes to the recruitment process, including treatment protocols with Minoxidil, Finasteride, and RU58841.

community Breezula Phase 3 confusion - did they change something?

8 upvotes 7 months ago

Breezula's phase 2 showed reduced efficacy after 6 months, but phase 3 had positive results, causing confusion about any changes made to the drug. There is frustration over the long timeline for hair loss treatments, with some users expressing more interest in other potential treatments like GT-20029.

community Do you get a shedding phase when you change from fin to dut?

in Finasteride/Dutasteride 1 upvotes 5 months ago

A user is considering switching from finasteride to dutasteride due to unsatisfactory results and is concerned about experiencing another shedding phase. Another user recently made the switch and will update on their experience.

community What is the chance that the pp405 molecule gets leaked to the grey market in phase 3?

18 upvotes 11 months ago

The conversation discusses the potential availability and use of the pp405 molecule for hair loss treatment, with concerns about its legitimacy and safety on the grey market. Participants also mention using products from Umbrella Labs and discuss the concentration and production costs of pp405.

community Chances of GT20029 hitting the black market?

in Treatment 11 upvotes 2 years ago

The conversation is about the potential availability of GT20029 on the black market and whether users would try it. Participants advise waiting for phase 3 trial results to ensure safety and efficacy.

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Learn

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learn Finasteride

Finasteride Results Timeline: How Long It Takes to Work, Shedding Phases, and Expected Outcomes Trial data and community reports both put the first visible changes on finasteride at roughly 3 to 6 months, with the clearest results between 6 and 12 months; an early shedding phase is common and usually temporary. The benefit lasts only while the drug is taken, and it is prescription-only.

learn Fluridil

How long does it take to see results with Fluridil in progressive hair loss? No published study measures how long fluridil takes to show a visible change; the single double-blind trial (43 men, 2% fluridil) reported a rise in the proportion of hairs in the growth phase at three and nine months, and community reports describe stabilization rather than regrowth.

learn Pyrilutamide

highly targeted anti-androgen that might have minimal systemic effects

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn sh-Polypeptide-7

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