Final Phase in the Validation of the Cross-Cultural Adaptation of the Hair-Specific Skindex-29 Questionnaire Into Spanish: Sensitivity to Change and Correlation With the 12-Item Short-Form Health Survey

In 2019, a study involving 983 women with female-pattern hair loss validated the Spanish version of the Hair-Specific Skindex-29 (HSS-29) questionnaire, which assesses the impact of hair loss on health-related quality of life (HRQOL). The study showed that after 6 months of treatment with a nutritional supplement, the mean HSS-29 score significantly decreased, indicating an improvement in HRQOL. The changes in HSS-29 scores also significantly correlated with changes in the 12-item Short-Form Health Survey (SF-12) scores, with Pearson correlation coefficients ranging from -0.1 to -0.4 (P < .001). This confirmed that the HSS-29 is sensitive to change and correlates with SF-12, making it a valid tool for Spanish-speaking women to measure the impact of female-pattern hair loss on their quality of life.