22 citations
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October 2001 in “Biochemical Pharmacology” This study found that GI198745 acts as a time-dependent inhibitor of rat 5α-reductase type 2 but a rapid-equilibrium inhibitor of type 1, potentially making it more effective than finasteride in preventing rat prostate growth.
4 citations
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May 2019 in “Asian Journal of Pharmaceutical Sciences” This study found that a dutasteride tablet formulation using cyclodextrin complex, solubilizing polymer, and surfactant achieved similar bioavailability in beagle dogs to that of a commercial capsule.
3 citations
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January 2015 in “Journal of drug assessment” This study found that five 0.1 mg dutasteride capsules are bioequivalent to one 0.5 mg dutasteride capsule in healthy adult males under fasting conditions, and both were well tolerated.
2 citations
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September 2011 in “Chiang Mai Medical Journal - เชียงใหม่เวชสาร” This study demonstrated that the 5-mg generic finasteride tablet is bioequivalent to the original tablet when tested in healthy Thai male volunteers.
January 2009 in “Chinese Journal of Drug Application and Monitoring” This study concluded that finasteride granules are bioequivalent to finasteride tablets based on pharmacokinetic evaluation in healthy male volunteers.