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    Glossary Pharmacogenetics

    study of how genes affect individual responses to medications

    Pharmacogenetics is the study of how an individual's genetic makeup affects their response to drugs. This field aims to tailor medical treatments to each person’s genetic profile, enhancing drug efficacy and minimizing adverse effects. It is also known as pharmacogenomics, and involves testing specific genes to predict how a patient will respond to certain medications.

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    1. Pharmacogenetic analysis of human steroid 5α reductase type II: comparison of finasteride and dutasteride Journal of Molecular Endocrinology · 2005 · 26 citations
    2. Pharmacogenetics of the Androgen Metabolic Pathway 2010
    3. The role of candidate pharmacogenetic variants in determining valproic acid efficacy, toxicity and concentrations in patients with epilepsy Frontiers in Pharmacology · 2024
    4. The efficacy and safety of valproic acid medications with controlled active ingredient release in adults in real clinical practice from the position of pharmacokinetic and pharmacogenetic approaches Nevrologiâ, nejropsihiatriâ, psihosomatika · 2017 · 5 citations
    5. Pharmacogenetic Determinants of Valproic Acid Efficacy, Toxicity, and Serum Levels in Genetic Generalized Epilepsy Specialty journal of Pharmacognosy Phytochemistry and Biotechnology · 2024
    6. Pharmacokinetics, toxicity, and activity of intravenous dextran sulfate in human immunodeficiency virus infection Antimicrobial Agents and Chemotherapy · 1991 · 142 citations
    7. ORIGINAL RESEARCH—ENDOCRINOLOGY: Comparison of the Steady‐State Pharmacokinetics, Metabolism, and Variability of a Transdermal Testosterone Patch Versus a Transdermal Testosterone Gel in Hypogonadal Men ˜The œjournal of sexual medicine · 2005 · 38 citations
    8. The effect of St. John’s wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men European Journal of Pharmaceutical Sciences · 2008 · 33 citations
    9. Pharmacokinetics of a new testosterone transdermal delivery system, TDS<sup>®</sup>‐testosterone in healthy males British Journal of Clinical Pharmacology · 2005 · 33 citations
    10. The Pharmacokinetics of 2.5- to 10-mg Oral Doses of Minoxidil in Healthy Volunteers The Journal of Clinical Pharmacology · 1989 · 25 citations
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