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Did you mean Orthokeratotic Hyperkeratosis?

GlossaryOrthokeratotic Hyperkeratosis

excessive buildup of outer skin layer without cell nuclei

Orthokeratotic Hyperkeratosis is a skin condition characterized by an excessive buildup of the outer layer of the skin, known as the stratum corneum, without the presence of nuclei in the keratinocytes. This results in thickened, often scaly skin. For professionals, it is important to note that this condition can be distinguished from parakeratotic hyperkeratosis, where nuclei are retained in the stratum corneum.

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Proliferative, Lymphocytic, Infundibular Mural Folliculitis and Dermatitis with Prominent Follicular Apoptosis and Parakeratotic Casts in Four Labrador Retrievers: Preliminary Description and Response to Therapy

research Proliferative, Lymphocytic, Infundibular Mural Folliculitis and Dermatitis with Prominent Follicular Apoptosis and Parakeratotic Casts in Four Labrador Retrievers: Preliminary Description and Response to Therapy

10 citations, April 2013 in “Veterinary dermatology”

A new skin disease in four Labrador retrievers responded well to immunosuppressive treatment.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 821 upvotes 5 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.