research Iron–Skin Axis: Exploring the Interplay between Iron Homeostasis and Skin Disorders
This review highlights the critical role of iron in skin functions and suggests potential dermatologic therapies targeting the iron-skin axis.
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5 / 1000+ resultsresearch Periodontitis, Psoriasis and Other Skin Disorders: Epidemiological and Mechanistic Evidence
In this narrative review, the authors found epidemiological evidence suggesting a positive link between periodontitis and psoriasis, with treatment for periodontitis potentially reducing psoriasis severity over the short term, though causality and mechanisms remain unclear.
research 1115 Interrogating the gut-skin axis for acne and sebaceous gland health – a case study of nicotinic acid
This study found that while nicotinic acid significantly inhibited human sebaceous organoid growth in vitro, the predicted skin concentrations from gut microbiome-derived levels were far below the effective dose, suggesting high oral doses would be necessary for therapeutic effects.
research Oral delivery of marine shellfish supramolecule peptides for skin wound healing
This study found that oral administration of naturally safe active polypeptides from marine shellfish promoted scarless dermal wound healing in mice, potentially via effects on inflammation, fibroblast activity, and the "skin-gut" axis.
research Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA)
This case study reported significant but temporary hair regrowth and skin repigmentation in a patient with vitiligo and alopecia areata during treatment with oral ruxolitinib.
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5 / 1000+ resultscommunity Hair Loss “Cure” for Inflammation: Topical Roflumilast
Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.
community There’s nothing better on the horizon [RANT]
There is skepticism about new hair loss treatments, with the belief that current options like minoxidil, finasteride, and hair transplants are the best available. Concerns are raised about the systemic side effects of androgen-related treatments, even those marketed as topical, and doubts about the effectiveness of emerging treatments like clascoterone.
community KX826 is better than RU58841. A legitimate option for those who cant use fin or dut.
KX826 is considered a legitimate option for those who cannot use finasteride or dutasteride, but many users report it as ineffective compared to RU58841. RU58841 is favored by some due to anecdotal evidence of effectiveness, despite the lack of published clinical data.
community Is Finasteride the only way to reduce scalp DHT?
A 24-year-old male experienced side effects like low libido and ED after starting finasteride post-hair transplant and is seeking alternatives to reduce scalp DHT. Suggestions include topical finasteride, Xpecia, DHT-reducing shampoos, and switching to dutasteride, with some users reporting fewer side effects with these alternatives.
community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment
The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.
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5 / 16 results- How does topical Estradiol compare to oral Estradiol in treating alopecia? No study has compared topical and oral estradiol for hair loss, and estradiol applied to skin is still absorbed into the blood. Either form needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.
- Is Thymosin Beta 4 being explored more as a topical treatment or as a systemic (oral or injectable) approach for hair loss? Thymosin Beta 4 has been tested for hair growth only in animals, mostly applied to the skin; there are no human hair-loss trials by any route. Injectable TB-500 sold online is unapproved and flagged by the FDA for safety risks.
- Is there a difference between taking folic acid supplements and using folic acid in topical hair products? Oral folic acid uses the body's normal absorption route and can correct a measured deficiency, but no published trial shows it treats hair loss; topical folic acid has no human evidence for hair growth, and no published human data show how much of it a plain shampoo or serum gets through the skin barrier.
- Is Niacinamide better to apply topically or to take as a supplement for hair growth? Neither topical nor oral niacinamide has been shown to grow hair. Topical niacinamide has been studied mainly on facial skin.
- GHK-Cu: Does it have side effects or is it completely safe? For topical cosmetic use, one 24-hour study in cultured skin cells found a low potential for irritation, but no clinical trial has characterised its side effects on the scalp. Injected or oral GHK-Cu has no published human safety data, and the FDA lists injectable GHK-Cu among compounding substances that may present significant safety risks.
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Hair TransplantHair Loss TreatmentsDermatologyORA Skin ClinicsHyderabad, Telangana · IN
Hair TransplantMinnesota Oral & Facial SurgeryMinneapolis, MN · US
Hair TransplantKansas City Facial & Oral SurgeryLee's Summit, MO · US
TrichologySkinline Clinic | Klinika trychologii, kosmetologii i medycyny estetycznej oraz SPAWarsaw · PL
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