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research Oral ruxolitinib induces hair regrowth in patients with moderate-to-severe alopecia areata

196 citations , September 2016 in “JCI insight”

This study explored the effectiveness of the oral JAK1/2 inhibitor ruxolitinib in treating patients with moderate-to-severe alopecia areata, building on prior success with JAK inhibitors in mice, but results are not reported in this abstract.

research Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails

179 citations , October 2018 in “American Journal of Clinical Dermatology”

This review outlines various dermatologic adverse events associated with targeted therapies and immunotherapies, emphasizing the need for collaboration between dermatologists and oncologists to manage these effects effectively; it reports no new clinical findings.

research Treatment of female pattern hair loss with oral antiandrogens

179 citations , March 2005 in “British Journal of Dermatology”

This study found that 88% of women with female pattern hair loss who received oral antiandrogens saw no progression or improvement in their condition.

research Placebo-controlled oral pulse prednisolone therapy in alopecia areata

141 citations , February 2005 in “Journal of the American Academy of Dermatology”

In this study, oral prednisolone pulse therapy led to significant hair regrowth in some patients with extensive alopecia areata, whereas no improvement was seen in the placebo group.

research Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review

117 citations , February 2017 in “American Journal of Clinical Dermatology”

This systematic review concluded that the support for using spironolactone at commonly prescribed doses is based on evidence of limited quality.

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Community Join

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community Facial bloating/aging on oral Min

4 upvotes 3 days ago

Oral minoxidil can cause facial bloating, leading to a puffy appearance. Some users report improvement after stopping the medication.

community Oral Fin to Dut switch, Libido Change timeline?

4 upvotes 4 days ago

The user switched from oral finasteride to dutasteride due to libido issues and is seeking advice on the timeline for libido recovery and potential hair gains. Some users suggest exercise to alleviate side effects, while others discuss the rarity of sexual side effects and recommend switching back to finasteride if issues persist.

community Oral min Australia ? Am I okay to be quartering 10mg

1 upvotes 1 week ago

A user in Sydney is taking oral finasteride and minoxidil for hair loss and is quartering 10mg minoxidil pills to achieve a 2.5mg dose, seeking advice on obtaining smaller doses or reliable pharmacies. They prefer not to use compounded pills and are concerned about dosing accuracy and pill storage.

community Oral Min, do you split the dose?

2 upvotes 1 week ago

The conversation discusses using oral Minoxidil (OM) and finasteride for hair loss, with the original poster considering splitting the OM dose to potentially improve results. Other users suggest trying topical treatments like dutasteride and minoxidil, and one user mentions adding kx826.

community Oral minoxidil not doing anything

10 upvotes 1 week ago

The user has been using finasteride for two years and added oral minoxidil a year ago but hasn't seen additional results. They are considering trying minoxidil foam, while others suggest adjusting the minoxidil dosage or exploring other underlying causes of hair loss.

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Learn

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learn Keratin

Can keratin supplements taken orally improve hair growth, or are they only useful topically? Oral keratin supplements do not directly improve hair growth.

learn Procyanidin

Can Procyanidin supplements taken orally help strengthen existing hair and prevent shedding? Oral procyanidin supplements may help strengthen hair and reduce shedding.

learn Tofacitinib

How does tofacitinib differ when used orally versus topically in hair loss treatment research? Oral tofacitinib acts on immune signalling throughout the body and has the stronger regrowth evidence in alopecia areata, alongside an FDA boxed warning; topical tofacitinib aims to act only on the scalp, but the human evidence is a handful of small compounded-formulation studies with no large randomized trial. Neither route is approved for hair loss, and regrowth generally reverses after treatment stops.

learn Vitamin E

Is it better to take Vitamin E orally or apply it topically for hair loss? Oral mixed tocotrienols have one small randomized human trial reporting increased hair count; topical vitamin E has no human trial for pattern hair loss, only a 1965 rabbit study. Neither is approved for hair loss, and high-dose vitamin E carries bleeding risk.

learn zinc PCA

Should zinc be taken orally or applied topically for better results in hair growth? Oral zinc supplementation is generally more effective for promoting hair growth than topical application.

learn Spironolactone

powerful topical and oral anti-androgen used mostly by women

learn Bicalutamide

a nonsteroidal anti-androgen, most commonly used orally for women

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Clinics

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Experts

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