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research Watching stem cells at work with a flexible multiphoton tomograph

February 2012 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE”

This study observed nestin-GFP expressing stem cells in the hair follicle bulge of living mice using high-resolution in-vivo multiphoton tomography, allowing migration tracking within their natural skin environment.

research Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies

2 citations , June 2020 in “Journal of Investigative Dermatology”

This article reviews the steps and methods involved in preparing skin tissues for three-dimensional volumetric imaging, highlighting its potential to provide detailed insights into skin structure not possible with traditional 2D histology, but reports no new findings.

research Confocal Laser Scanning Microscopy as a Tool for the Investigation of Skin Drug Delivery Systems and Diagnosis of Skin Disorders

4 citations , March 2013 in “InTech eBooks”

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

research Preparation of Mohs Micrographic Surgery Frozen Sections: Three New Pearls Leading to a Simplified, More-Effective Process

4 citations , May 2013 in “Dermatologic Surgery”

Three new techniques simplify and improve the preparation of tissue samples for skin cancer surgery.

research Immunofluorescence Tomography: High-resolution 3-D reconstruction by serial-sectioning of methacrylate embedded tissues and alignment of 2-D immunofluorescence images

8 citations , February 2019 in “Scientific Reports”

This article describes the immunofluorescence tomography method to achieve high-resolution 3-D reconstruction of epithelial tissues and reports no clinical results.

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community What's the general consensus on microneedling here?

in Microneedling 21 upvotes 2 years ago

The conversation discusses microneedling for hair loss, focusing on optimal needle depth and frequency. Users report varying practices, with some using Minoxidil after microneedling and others suggesting different depths and frequencies based on personal tolerance.

community Opinions on best microneedling protocol? Some thoughts...

11 upvotes 3 years ago

Microneedling can enhance hair growth by improving minoxidil absorption and stimulating blood flow. Users discuss optimal needle depths, with some favoring shallow frequent needling for better absorption and others preferring deeper needling for stem cell activation.

community Verteporfin and Microneedling

in Treatments 2 years ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

community 40M 7 months on 1mg Fin. Debating if I should also start Min

in Progress Pictures 17 upvotes 5 months ago

A 40-year-old man has been using 1mg finasteride for 7 months and is considering starting minoxidil. Users suggest adding microneedling and discuss the effectiveness and side effects of various treatments, including oral minoxidil and ketoconazole shampoo.

community DHT Itch is real. The connection between Acne and Male Pattern Baldness shows this

in Research/Science 64 upvotes 3 years ago

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

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