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    Glossary Opioids

    drugs that relieve pain by binding to brain receptors

    Opioids are a class of drugs that include both natural and synthetic substances derived from the opium poppy plant, as well as synthetic analogs. They are primarily used for pain relief but can also produce euphoria, which makes them prone to misuse and addiction. Common examples include morphine, heroin, and prescription painkillers like oxycodone and hydrocodone. Opioids work by binding to specific receptors in the brain and nervous system to reduce the perception of pain.

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    1. Allopregnanolone (AP) induces opioid inhibition of hypothalamo-pituitary-adrenal (HPA) axis responses to interleukin-1β (IL-1β) in pregnancy Experimental and Clinical Endocrinology & Diabetes · 2005 · 1 citations
    2. Sex Differences in Opioid-Mediated Effects: Role of Androgens Authorea (Authorea) · 2020
    3. S1 OPIOID RECEPTOR AGONISTS AND SERUM PROSTATE SPECIFIC ANTIGENE LEVEL: IS THERE A ROLE FOR PROSTATE CANCER CONTROL AND CHEMOPREVENTION? European Urology Supplements · 2010
    4. Central Opioid Inhibition of Neuroendocrine Stress Responses in Pregnancy in the Rat Is Induced by the Neurosteroid Allopregnanolone Journal of Neuroscience · 2009 · 123 citations
    5. Allopregnanolone and Induction of Endogenous Opioid Inhibition of Oxytocin Responses to Immune Stress in Pregnant Rats Journal of Neuroendocrinology · 2012 · 41 citations
    6. An Overlooked Sequela of Long-Term Opioid Analgesic Use: A Case Report on Central Adrenal Insufficiency Journal of the Endocrine Society · 2021
    7. Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn Neuron · 2014 · 140 citations
    8. Hair Growth Promotion by δ-Opioid Receptor Activation Biomolecules & Therapeutics · 2021 · 1 citations
    9. An exploratory analysis of 5‐alpha reductase inhibitors and risk of opioid use disorder among male Medicare beneficiaries receiving prescription opioid medications American Journal on Addictions · 2025
    10. The Opioid Receptor Influences Circadian Rhythms in Human Keratinocytes through the β-Arrestin Pathway Cells · 2024
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    1. Quitting kratom stopped my hairloss by 80% Reddit · 18 Aug 2024

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