74 citations
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January 2011 in “Reproductive Biology and Endocrinology” This study suggests testosterone gel administered for one year to male chronic pain patients receiving morphine may improve sexual function and mental health, despite limited effects on overall pain scores.
25 citations
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September 2005 in “International Journal of Developmental Neuroscience” This study found that in rats, morphine exposure may increase 5alpha-reductase activity in the CNS, leading to decreased testosterone levels, an effect blocked by finasteride.
15 citations
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March 2007 in “Hormones and Behavior” Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.
4 citations
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April 2009 in “Journal of Pain” Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.
63 citations
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August 1996 in “Forensic Science International” In this study, bleaching and perming were found to significantly reduce opiate concentrations in both spiked and naturally opiate-positive human hair samples.