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    Glossary Opioids

    drugs that relieve pain by binding to brain receptors

    Opioids are a class of drugs that include both natural and synthetic substances derived from the opium poppy plant, as well as synthetic analogs. They are primarily used for pain relief but can also produce euphoria, which makes them prone to misuse and addiction. Common examples include morphine, heroin, and prescription painkillers like oxycodone and hydrocodone. Opioids work by binding to specific receptors in the brain and nervous system to reduce the perception of pain.

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    Research 30 of 457

    1. Allopregnanolone (AP) induces opioid inhibition of hypothalamo-pituitary-adrenal (HPA) axis responses to interleukin-1β (IL-1β) in pregnancy Experimental and Clinical Endocrinology & Diabetes · 2005 · 1 citations
    2. Sex Differences in Opioid-Mediated Effects: Role of Androgens Authorea (Authorea) · 2020
    3. S1 OPIOID RECEPTOR AGONISTS AND SERUM PROSTATE SPECIFIC ANTIGENE LEVEL: IS THERE A ROLE FOR PROSTATE CANCER CONTROL AND CHEMOPREVENTION? European Urology Supplements · 2010
    4. Central Opioid Inhibition of Neuroendocrine Stress Responses in Pregnancy in the Rat Is Induced by the Neurosteroid Allopregnanolone Journal of Neuroscience · 2009 · 123 citations
    5. Allopregnanolone and Induction of Endogenous Opioid Inhibition of Oxytocin Responses to Immune Stress in Pregnant Rats Journal of Neuroendocrinology · 2012 · 41 citations
    6. An Overlooked Sequela of Long-Term Opioid Analgesic Use: A Case Report on Central Adrenal Insufficiency Journal of the Endocrine Society · 2021
    7. Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn Neuron · 2014 · 140 citations
    8. Hair Growth Promotion by δ-Opioid Receptor Activation Biomolecules & Therapeutics · 2021 · 1 citations
    9. An exploratory analysis of 5‐alpha reductase inhibitors and risk of opioid use disorder among male Medicare beneficiaries receiving prescription opioid medications American Journal on Addictions · 2025
    10. The Opioid Receptor Influences Circadian Rhythms in Human Keratinocytes through the β-Arrestin Pathway Cells · 2024
    11. ADVERSE EFFECTS OF OPIOID ANALGESIC DRUGS British Journal of Anaesthesia · 1987 · 183 citations
    12. The 5α-reductase inhibitor finasteride reduces opioid self-administration in animal models of opioid use disorder Journal of Clinical Investigation · 2021 · 8 citations
    13. ODP056 The Treatment of Opioid Addiction Leading to Secondary Adrenal Insufficiency Journal of the Endocrine Society · 2022
    14. Long-term opioid ADR management in cancer patients Reactions Weekly · 1994
    15. The 5α-reductase inhibitor finasteride reduces opioid self-administration bioRxiv (Cold Spring Harbor Laboratory) · 2020
    16. ADVANCES IN THE TREATMENT OF ALCOHOL, OPIOID, AND CANNABIS ADDICTION Wiadomości Lekarskie · 2024
    17. Effect of non-steroidal anti-inflammatory drugs on post-surgical complications against the backdrop of the opioid crisis Burns & Trauma · 2018 · 36 citations
    18. Therapeutic indications and other use-case-driven updates in the drug ontology: anti-malarials, anti-hypertensives, opioid analgesics, and a large term request Journal of Biomedical Semantics · 2017 · 11 citations
    19. Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells 2010 · 77 citations
    20. Harnessing neuroendocrine controls of keratin expression: A new therapeutic strategy for skin diseases? BioEssays · 2014 · 26 citations
    21. The association of medications and supplements with human male reproductive health: a systematic review Fertility and Sterility · 2023 · 4 citations
    22. Low-dose naltrexone: a novel adjunctive treatment in symptomatic alopecias? Dermatology Online Journal · 2019 · 4 citations
    23. Iron Deficiency Anemia Pruritus: A Review with Proposed Mechanisms of Action Skin · 2024
    24. Neuroendocrine Controls of Keratin Expression in Human Skin IntechOpen eBooks · 2018
    25. S2 PSA: RELIABLE OR NOT RELIABLE? European Urology Supplements · 2010
    26. The Opiate Antagonist, Naltrexone, in the Treatment of Trichotillomania Journal of Clinical Psychopharmacology · 2013 · 69 citations
    27. Role of neurosteroid allopregnanolone on age-related differences in exercise-induced hypoalgesia in rats Journal of pharmacological sciences · 2018 · 4 citations
    28. A practical approach to feline symmetrical alopecia In Practice · 1998 · 4 citations
    29. Cutaneous Manifestations of Chronic Kidney Disease: A Narrative Review Journal of Biosciences and Medicines · 2026
    30. Expression of μ-Opiate Receptor in Human Epidermis and Keratinocytes Journal of Investigative Dermatology · 1998 · 111 citations