research S2 PSA: Reliable or Not Reliable?
PSA testing is a reliable method for detecting prostate cancer, and opioids may lower PSA levels, but triglycerides don't affect prostate cancer risk.
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research Sex Differences in Opioid-Mediated Effects: Role of Androgens
Men and women react differently to opioids, with hormones potentially influencing these differences.
research Harnessing Neuroendocrine Controls of Keratin Expression: A New Therapeutic Strategy for Skin Diseases?
Using neurohormones to control keratin can lead to new skin disease treatments.
research Iron Deficiency Anemia Pruritus: A Review with Proposed Mechanisms of Action
Iron deficiency anemia can cause itching, which often improves with iron supplements.
research Neuroendocrine Controls of Keratin Expression in Human Skin
Neurohormones help control skin health and could treat skin disorders.
research Alopecia and Associated Toxic Agents: A Systematic Review
Thallium, mercury, selenium, and colchicine strongly cause hair loss.
research Generalized Pruritus in Primary Sclerosing Cholangitis: Implications of Histamine Release by Lysophosphatidic Acid
A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.
research Pharmacologic Management of Acute Attacks of Migraine and Prevention of Migraine Headache
Use NSAIDs for immediate migraine relief and β-blockers for prevention; tailor treatment to the individual.
research Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn
Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.
research Effect of Non-Steroidal Anti-Inflammatory Drugs on Post-Surgical Complications Against the Backdrop of the Opioid Crisis
NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.
research Adverse Effects of Opioid Analgesic Drugs
Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.
research The 5α-Reductase Inhibitor Finasteride Reduces Opioid Self-Administration in Animal Models of Opioid Use Disorder
Finasteride reduces opioid use and withdrawal symptoms in animals.
research Low-Dose Naltrexone: A Novel Adjunctive Treatment in Symptomatic Alopecias?
Low-dose naltrexone might be a cheap and effective additional treatment for hair loss with scalp discomfort due to its anti-inflammatory effects and few side effects.
research Walrus
Anesthetizing walruses is difficult and risky due to their size and sudden health changes.
research This Week in JAMA: March 7, 2012 Issue Highlights
Early surgery reduces seizure risk in drug-resistant epilepsy; testosterone to DHT conversion doesn't affect muscle anabolism; veterans with PTSD likely to have riskier opioid use; bevacizumab helps in hereditary bleeding disorder.
research Hair
Hair analysis can detect drug use but is costly and interpretation is complex.
research Urethral PSA Levels After Radical Prostatectomy
Higher urethral PSA levels after prostate removal surgery may be linked to more hair loss and higher PSA levels post-surgery.
research S1 Opioid Receptor Agonists and Serum Prostate-Specific Antigen Level: Is There a Role for Prostate Cancer Control and Chemoprevention?
Opioid use may lower PSA levels, suggesting a possible role in prostate cancer control; PSA testing is useful for detecting prostate cancer; serum triglycerides are not linked to prostate cancer risk; and higher urethral PSA levels may be associated with local hormone activity.
research The 5α-Reductase Inhibitor Finasteride Reduces Opioid Self-Administration
Finasteride may help reduce opioid use.
research Forum
The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
research The Neurobiology of Sexual Function
Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.
research Cannabinoids: Current and Future Options to Treat Chronic and Chemotherapy-Induced Neuropathic Pain
Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
research Safety and Efficacy of Transdermal Testosterone for Treatment of Hypoactive Sexual Desire Disorder
Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.
research Oral Low-Dose Naltrexone in the Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: An Uncontrolled Open-Label Prospective Study
Low-dose naltrexone may help reduce redness in certain scalp conditions.
research Managing the Adverse Effects of Cytotoxic Chemotherapy at the Level of Primary Healthcare
Primary healthcare clinics are key in managing chemotherapy side effects using various medications and treatments.
research The Use and Abuse of Oral Contraceptive Pills Among Males: A Mixed-Method Explanatory Sequential Study Over Jordanian Community Pharmacists
Many males in Jordan misuse oral contraceptive pills for hair growth, muscle gain, and acne treatment.
research Endocrine Disorders and Infertility
Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.
research Antinociceptive Activity of Adiantum Capillus in Experimental Animals
Adiantum capillus extract reduces pain and swelling in animals.
research Mental, Behavioral, and Physical Effects of Power-Enhancing Drugs in Chronic Users
Power-enhancing drugs can cause mood swings, aggression, anxiety, and physical side effects, questioning their overall benefits.
research Is Radical Prostatectomy the Best Choice for Patients with Locally Advanced Prostate Cancer?
The document does not confirm if radical prostatectomy is the best treatment for locally advanced prostate cancer.