research Dynamic Regulation of Retinoic Acid-Binding Proteins in Developing, Adult, and Neoplastic Skin Reveals Roles for β-Catenin and Notch Signaling
Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.
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5 / 1000+ resultsresearch Pleiotropic Role of Notch Signaling in Human Skin Diseases
Notch signaling disruptions can cause various skin diseases.
research Jagged-1+ Skin Tregs Modulate the Innate Immune Response to Wound Healing
Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.
research Regulating Hair Follicle Stem Cells
Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
research Adult Epidermal Notch Activity Induces Dermal Accumulation of T Cells and Neural Crest Derivatives Through Upregulation of Jagged 1
Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
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5 / 66 resultscommunity Shoutout to Zinc pyrithione and Piroctone olamine
Zinc pyrithione and piroctone olamine are effective for reducing hair shedding, possibly more so than ketoconazole. There is a concern about zinc pyrithione shampoo interfering with minoxidil, but it's unclear if this is proven.
community Joined the Dutasteride Master Race
Dutasteride and finasteride are discussed for hair loss treatment, with users sharing experiences and debating their effectiveness and side effects. Celebrities are noted as common users, and there is debate over which treatment is superior.
community Front page article at The New York Times (biggest circulation in the world) regarding notable results with oral minoxidil is a pretty big deal
This conversation discusses the potential benefits of using oral minoxidil and finasteride to treat hair loss, with some users sharing their own experiences in taking the medications. Others express concerns about the safety of these treatments.
community Before and After - My journey so far
A 28-year-old used oral finasteride and minoxidil, and underwent two hair transplants in Turkey, with a total of 3150 grafts, resulting in a natural-looking hairline. The first procedure cost £3300, and the second was a free touch-up, with additional costs for flights and accommodation.
community Pyrilutamide binding affinity is similar to RU
Comparing the effectiveness of RU58841, Pyrilutamide and CB-03-01 as treatments for hair loss, with people discussing different aspects such as binding affinity, time of inhibition, safety data and cost.