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5 / 1000+ resultsresearch Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack
The study explored how hair follicles (HFs) maintain immune privilege (IP) to avoid natural killer (NK) cell attacks, which typically target cells with low MHC class I expression. It was found that HFs actively suppress NK cells, with the HF epithelium expressing the NK cell inhibitor macrophage migration inhibitory factor. In healthy individuals, fewer NK function-activating receptors and more inhibitory receptors were present compared to those with alopecia areata (AA), an autoimmune disease linked to a breakdown of HF-IP. AA patients showed increased NK cell activity around hair follicles, suggesting a defect in NK cell inhibition that contributes to the disease's pathogenesis. This defect was previously unreported and highlighted the need for considering NK cell activity in AA management.
research Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-Conditioning
Changing how mesenchymal stromal cells are grown can improve their healing abilities.
research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research A Novel Therapeutic Paradigm for Patients with Extensive Alopecia Areata
New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
research Regenerative Medicine Strategies for Hair Growth and Regeneration: A Narrative Review of Literature
New regenerative treatments for hair loss show promise but need more research for confirmation.
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3 / 3 resultscommunity COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men
Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.
community Is 2years+ telogen effluvium possible?
The user has been losing hair for over two years despite taking dutasteride and RU58841, even increasing dutasteride to 2.5mg. They are questioning if their hair loss could be due to telogen effluvium instead.
community found my progress pictures on a scam account
A user discovered their hair regrowth progress pictures were used in a scam promoting a fake "elixir." The user clarified that their actual results came from using finasteride and minoxidil for three months.