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GlossaryNeurogenic Inflammation

inflammation triggered by nerve-released chemicals causing redness and pain

Neurogenic inflammation is a type of inflammation triggered by the nervous system. It occurs when nerve fibers release certain chemicals, like substance P and calcitonin gene-related peptide (CGRP), which cause blood vessels to expand and immune cells to become activated, leading to redness, swelling, and pain. This process is often involved in conditions like migraines, asthma, and some skin disorders.

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research Frontal Fibrosing Alopecia and Increased Scalp Sweating: Is Neurogenic Inflammation the Common Link

15 citations, January 2015 in “Skin Appendage Disorders”

Increased scalp sweating in frontal fibrosing alopecia may be linked to local skin inflammation.

research Neuroimmunoendocrine Circuitry of the Brain-Skin Connection

293 citations, November 2005 in “Trends in Immunology”

Stress can worsen skin conditions and stop hair growth by affecting the body's stress response system.

research Biological Effects of Electrical Epilation on Human Hair Follicles and Perifollicular Skin Ex Vivo

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Electrical epilation damages hair follicles and surrounding skin, likely preventing hair regrowth.

research Neuroimmunology of Stress: Skin Takes Center Stage

375 citations, July 2006 in “Journal of Investigative Dermatology”

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

research Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

66 citations, July 2007 in “Journal of Molecular Medicine”

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

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community How are you managing sex life when applying to topical minoxidil?

in Minoxidil 99 upvotes 1 year ago

User asks how to manage sex life while using topical minoxidil for hair loss. Responses suggest various strategies, including using finasteride, applying minoxidil before or after sex, and avoiding certain positions.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 8 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Where do you guys get your stemoxydine from?

in Product 2 upvotes 2 weeks ago

Stemoxydine is available in L'Oréal's Serioxyl and Dercos Neogenic products, which can be found on Amazon, Ulta, or L'Oréal's website. A user is selling three bottles of L'Oréal Stemoxydine.

community Let's discuss experimental - RU58841, Dutasteride, and Others

6 upvotes 9 years ago

Discussing and researching different treatments for hair loss, including RU58841, Dutasteride, Spironolactone, Retin-A, Stemoxydine (Neogenic), Copper peptides, Superoxide Dismutase, NANO, and Eucapil.

community 7 months update - 1 mg fin, topical min

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