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GlossaryNeural Crest Stem Cells

originate from the neural crest and can become various cell types

Neural Crest Stem Cells (NCSCs) are a type of multipotent stem cell that originate from the neural crest, a transient structure in vertebrate embryos. These cells have the remarkable ability to differentiate into a diverse range of cell types, including neurons, glial cells, melanocytes, and even some types of connective tissue. This versatility makes them crucial for the development of various tissues and organs, and they are a significant focus in regenerative medicine and developmental biology research.

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research Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells

10 citations, January 2014 in “BioMed research international”

Rat whisker cells can help turn other cells into nerve cells and might be used to treat brain injuries or diseases.

research Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis

11 citations, February 2019 in “Stem cells international”

Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.

research Human Epidermal Neural Crest Stem Cells as a Source of Schwann Cells

44 citations, January 2015 in “Development”

Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.

research CD34 Defines Melanocyte Stem Cell Subpopulations With Distinct Regenerative Properties

41 citations, April 2019 in “PLOS genetics”

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

research CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance

11 citations, March 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

A specific group of skin stem cells was found to help maintain hair follicle cells.

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community How much dht does Nizoral shampoo block?

in Ketoconazole 101 upvotes 3 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, and Nizoral shampoo. Nizoral's effectiveness is debated, with some suggesting it works as a weak antagonist for androgen receptors, while others attribute its benefits to anti-fungal and anti-inflammatory properties.

community I enjoy taking finasteride every day

in Finasteride/Dutasteride 241 upvotes 7 months ago

Users discuss their positive experiences with finasteride for hair loss, mentioning halted hair loss, hair regrowth, and improved self-esteem. Some express satisfaction in taking action against baldness, while others note increased libido and energy.

community Anyone excited for CosmeRNA coming this month?

in Product 171 upvotes 1 year ago

CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

community 1 month Pyrilutamide. A non responders story to everything.

in Research/Science 218 upvotes 2 years ago

My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.

community I have hairy legs and arms, and the hair grows 2+ inches long- Can I transplant it all to my head?

in Transplants 442 upvotes 4 months ago

The conversation discusses the possibility of transplanting leg and arm hair to the scalp for hair loss treatment. Minoxidil is mentioned as a potential aid for hair growth, but concerns about the effectiveness and appearance of body hair on the head are raised.

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