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research Neurogenic Inflammation in Stress-Induced Termination of Murine Hair Growth Is Promoted by Nerve Growth Factor

108 citations , July 2004 in “American Journal of Pathology”

This study suggests that nerve growth factor plays a crucial role in the stress-induced termination of hair growth in mice, and its antagonism might offer a therapeutic approach to mitigate stress-related hair loss.

research Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways

66 citations , July 2007 in “Journal of Molecular Medicine”

This study in mice demonstrated that stress or nerve growth factor injection increases sensory neuron activity related to skin innervation, suggesting a strong connection between stress perception and neurogenic skin inflammation.

research Nerve growth factor and burn wound healing: Update of molecular interactions with skin cells

11 citations , August 2023 in “Burns”

This review explores the molecular mechanisms through which NGF may enhance burn wound healing by reducing healing time and improving scar quality, but it presents no new clinical results.

research Synthesis of nerve growth factor mRNA in cultures of developing mouse whisker pad, a peripheral target tissue of sensory trigeminal neurons.

5 citations , March 1993 in “The Journal of Cell Biology”

This study concluded that the increase in NGF mRNA levels during mouse whisker pad development is influenced by soluble factors produced within the tissue, rather than linked to epidermal differentiation.

research Nerve growth factor regulates the proliferation of cashmere goat outer root sheath cells through the activation of cAMP-binding protein

1 citations , July 2019 in “Small ruminant research”

This study suggests that the NGF/TrkA/CREB system plays a crucial role in promoting outer root sheath cell proliferation in cashmere goats, which may aid in marker-assisted breeding.

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community I Guess balding is cured so should we close subreddit and move to hairstyling photos 😁 Botox-like nerve blocking reveals potential way to fully regenerate skin without scarring

6 months ago

Baldness is difficult to cure because current treatments like finasteride, dutasteride, and minoxidil only prevent hair shedding, and new developments are mostly ineffective. Botox shows potential in aiding skin regeneration and hair growth, but maintenance therapy with treatments like dutasteride and minoxidil may still be necessary.

community Weird response to microneedling

in Microneedling 40 upvotes 1 year ago

Microneedling can cause sneezing and eye tearing due to nerve stimulation, particularly near the temples and forehead. Some users find it lessens over time, while others prefer using finasteride and minoxidil for hair growth.

community Hair loss research focused on chemistry for decades because we misunderstood the mechanics of growth.

51 upvotes 7 months ago

Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.

community BPC-157 and Angiogenesis. Bro-Science-Execution-Plan

in Research/Science 13 upvotes 1 year ago

BPC-157 may promote hair growth by increasing angiogenesis, similar to how Minoxidil works, though no direct research confirms this yet. Users report combining BPC-157 with Minoxidil and finasteride for better results, but concerns about long-term safety exist.

community GT20029 - Promising phase II results

16 upvotes 2 years ago

GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

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