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research Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues II. Concomitant and mutually exclusive synthesis of trichocytic and epithelial cytokeratins in diverse human and bovine tissues (hair follicle, nail bed and matrix, lingual papilla, thymic reticulum)

187 citations , May 1988 in “Differentiation”

This study found that trichocytic cytokeratins, typically found in hair, are also present in nails, filiform papillae of the tongue, and the epithelial reticulum of the thymus.

research Videodermoscopy of the hyponychium in nail bed psoriasis

76 citations , March 2008 in “Journal of the American Academy of Dermatology”

This study found that videodermoscopy can help diagnose nailbed psoriasis by revealing distinctive hyponychial capillary patterns, which correlated with disease severity and response to treatment.

research Heterogeneous red–white discoloration of the nail bed and distal onycholysis in a patient with COVID‐19

8 citations , May 2021 in “Journal of the European Academy of Dermatology and Venereology”

This case report describes a 23-year-old male patient with nail discoloration that may be associated with COVID-19, suggesting possible microvascular damage.

research Expression of hair keratins in the adult nail unit: an immunohistochemical analysis of the onychogenesis in the proximal nail fold, matrix and nail bed

110 citations , August 2004 in “British Journal of Dermatology”

In this study, researchers identified the ventral matrix as the primary source of nail plate formation, while the dorsal portion is generated by the apical matrix.

research Keratin expression in the normal nail unit: markers of regional differentiation

119 citations , January 2000 in “British Journal of Dermatology”

This study found that keratin expression patterns vary within nail unit structures, with the nail matrix uniquely expressing the acidic hair-type keratin Ha1.

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community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

124 upvotes 2 years ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community If PP405 works it will be fkn impossible to buy it.

103 upvotes 10 months ago

PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.

community For people with overly oily hair, does topical finasteride/dutasteride/antiandrogens (like RU or Pyrilutamide) reduce sebum overproduction?

in Finasteride/Dutasteride 6 upvotes 3 years ago

The conversation discusses whether topical finasteride, dutasteride, or antiandrogens like RU58841 can reduce sebum overproduction as an early indicator of their effectiveness in treating hair loss. It suggests that while hair growth may take months to observe, a decrease in oiliness could be a quicker sign of a product's action.

community Why don’t more people use hair fibers?

in Product 527 upvotes 10 months ago

Hair fibers can effectively cover thinning hair when used with minoxidil and hairspray but require daily application and can be inconvenient in certain conditions. Some users prefer treatments like finasteride, dutasteride, microneedling, or wigs due to the maintenance and limitations of hair fibers.

community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

2264 upvotes 1 year ago

A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

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