This review discusses the role of norepinephrine release and protein kinase C activation in the development of benign prostatic hypertrophy, suggesting potential targets for new therapies, but it reports no new clinical results.
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September 2013 in “Molecular Medicine Reports” In this study, researchers developed a method to efficiently derive contractile smooth muscle cells from human hair follicle stem cells using TGF-β1 and PDGF-BB, which may advance vascular tissue engineering.
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September 2016 in “Journal of Cellular Biochemistry” This study found that under hypoxic conditions, hair follicle-associated pluripotent stem cells differentiated into cardiac muscle cells at a higher rate compared to normoxic conditions.
In this study, Smad4 deletion in satellite cells hindered skeletal muscle regeneration in adult mice and did not enhance regeneration in aged mice, indicating Smad4's crucial role in muscle repair.
This study found that Smad4 is crucial for satellite cell amplification during skeletal muscle regeneration, with aged cells exhibiting less Smad4 and reduced regenerative capability in mice.
