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GlossarymTOR pathway (mTORC1 signaling)

regulates cell growth and metabolism in response to nutrients

The mTOR pathway, short for the mechanistic target of rapamycin pathway, is a crucial cellular signaling pathway that regulates growth, metabolism, and survival in response to nutrients, growth factors, and other environmental cues. It plays a significant role in various biological processes, including cell proliferation, protein synthesis, and autophagy, and is implicated in conditions like cancer, diabetes, and neurodegenerative diseases.

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research A Review of the Impact of Calorie Restriction on Stem Cell Potency

4 citations, August 2021 in “The Malaysian journal of medical sciences/The Malaysian Journal of Medical Science”

Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.

research Establishment and Characterization of a Radiation-Induced Dermatitis Rat Model

16 citations, February 2019 in “Journal of Cellular and Molecular Medicine”

Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.

research Insulin Resistance and Skin Diseases

71 citations, January 2015 in “The Scientific World Journal”

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

research Mammalian Target of Rapamycin Complex 1 (mTORC1) May Modulate the Timing of Anagen Entry in Mouse Hair Follicles

28 citations, November 2012 in “Experimental dermatology”

A protein complex called mTORC1 likely affects when hair growth starts in mice.

research MTOR Signaling in Hair Follicle and Hair Diseases: Recent Progress

September 2023 in “Frontiers in medicine”

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

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