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GlossaryMitochondrial Membrane Potential

electrical voltage difference across the inner mitochondrial membrane

Mitochondrial Membrane Potential (Δψm) is the electrical voltage difference across the inner membrane of mitochondria, which is crucial for the production of ATP, the cell's main energy currency. This potential is generated by the movement of protons (H+ ions) across the membrane during cellular respiration and is essential for various cellular processes, including energy metabolism and apoptosis (programmed cell death).

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mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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research Disease Prevention and Alleviation by Human Myoblast Transplantation

5 citations, January 2016 in “Open Journal of Regenerative Medicine”

Myoblast transplantation shows promise for treating various muscle and heart conditions.

research Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization

222 citations, August 2014 in “Cell Metabolism”

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

research Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire

40 citations, March 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.

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community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 97 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 734 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

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