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Mitochondrial-Related Genes as Prognostic and Metastatic Markers in Breast Cancer: Insights from Comprehensive Analysis and Clinical Models

research Mitochondrial-related genes as prognostic and metastatic markers in breast cancer: insights from comprehensive analysis and clinical models

12 citations , September 2024 in “Frontiers in Immunology”

This study found that metabolism-related genes significantly impact the prognosis and metastasis in breast cancer, and the development of prediction models may guide personalized therapeutic strategies.

research MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters

1 citations , July 2023 in “Nature communications”

This study found that deleting the Mof gene in mouse skin leads to severe defects in skin cell self-renewal, differentiation, and hair follicle growth, indicating that MOF is crucial for mitochondrial and ciliary gene expression and essential for skin development.

research Identification of Hypoxia and Mitochondrial-related Gene Signature and Prediction of Prognostic Model in Lung Adenocarcinoma

6 citations , January 2024 in “Journal of Cancer”

In this study, researchers developed a prognostic model using 16 genes to predict lung adenocarcinoma prognosis, showing good predictive accuracy and potential clinical utility in guiding treatment decisions based on hypoxia and mitochondrial-associated gene expression.

Identification and Single-Cell Analysis of Prognostic Genes Related to Mitochondrial and Neutrophil Extracellular Traps in Bladder Cancer

research Identification and single-cell analysis of prognostic genes related to mitochondrial and neutrophil extracellular traps in bladder cancer

July 2025 in “Scientific Reports”

In this study, researchers identified six novel prognostic biomarkers for bladder cancer and developed a predictive model that effectively stratifies patients into high-risk and low-risk groups based on immune cell infiltration differences and gene expression.

research A young male with kidney damage from genetic mitochondrial disease: case report and literature review

August 2026 in “BMC Nephrology”

In this study, a young Chinese male with a specific mitochondrial mutation was reported to have proteinuria and renal dysfunction, with stable kidney function after treatment over 23 months.

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community Have people with aggressive balding genetics genuinely had any results after applying any natural remedies ie:rosemary oil,coconut oil,Onion Juice etc

in Research/Science 42 upvotes 2 years ago

Natural remedies like rosemary oil, coconut oil, and onion juice are generally seen as less effective compared to medical treatments like finasteride, minoxidil, and microneedling. Some users believe natural oils can help, but modern medicine is often more reliable.

community The mechanism of androgenic alopecia

36 upvotes 11 months ago

DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

community Thoughts on new drug PP405? Already reached phase 2

26 upvotes 1 year ago

PP405 is a new drug in Phase 2 trials for hair loss, generating cautious optimism among users. Some users are currently using finasteride and experiencing side effects, while others are skeptical about unapproved products being sold.

community If we can clone a sheep why we can't cure baldness till now

in Research/Science 181 upvotes 11 months ago

Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.

community How I recovered from 4+ years of severe balding ages 20-24 by dieting, lifestyle changes and ONLY using topical minoxidil

in Progress Pictures 473 upvotes 1 year ago

A user reversed severe hair loss with dieting, lifestyle changes, and topical minoxidil, highlighting reduced inflammation and body fat. The conversation debates finasteride's effectiveness and the impact of diet and lifestyle on hair health.

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mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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Hair System Specialist
Jane Genesi
Marlton, PA, United States

Jane Genesi