learn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
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5 / 6 resultslearn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
learn Cetirizine
popular antihistamine showing promise for hair loss as an anti-inflammatory and prostaglandin inhibitor
learn Tretinoin
the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil
learn Bicalutamide
a nonsteroidal anti-androgen, most commonly used orally for women
Research
5 / 1000+ results
research Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review
Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
research Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development
Mitochondrial reactive oxygen species are essential for skin and hair development.
research Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization
Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.
research Abnormal Neuronal Differentiation and Mitochondrial Dysfunction in Hair Follicle-Derived Induced Pluripotent Stem Cells of Schizophrenia Patients
Schizophrenia patients' stem cells show abnormal neuron development and mitochondrial issues.
research Antiretroviral Nucleoside and Nucleotide Analogues and Mitochondria
Some HIV treatments can harm mitochondria, potentially causing side effects like lactic acidosis and nerve damage.
Community Join
5 / 242 resultscommunity Solving Hair Loss with Research at MIT
Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.
community Update on taking hims spray. I cut my dose to EOD, 2-3 sprays; instead of 4 sprays everyday. Trying to mitigate any leakage of fin into bloodstream.
A user shared progress pictures and discussed their hair loss treatment, including using Hims spray with finasteride, oral finasteride, castor oil, and derma rolling. They reduced their Hims spray dose to every other day to minimize finasteride absorption into the bloodstream.
community A science based addition to your hair loss routine
Blocking the Mitochondrial pyruvate carrier and using aldose reductase inhibitors like Indian gooseberry and berberine may help with hair growth. Magnesium can also be added to increase NADPH.
community Best supplements to take while on fin to avoid sides?
The conversation discusses using zinc and iron supplements to mitigate side effects of finasteride. It also mentions that shedding is a normal part of the process and suggests a healthy diet, exercise, and sleep to support hair health.
community 17 and Balding- Need treatment help and input
A 17-year-old in the UK seeks advice on mitigating hair loss until finasteride becomes an option at 19. Recommendations include using Minoxidil and considering other treatments like specific shampoos and dietary changes.