77 citations
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July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology”
This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.
2 citations
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June 2023 in “Clinical Cosmetic and Investigational Dermatology”
In this study, post-treatment with DCO was found to speed up epidermal wound healing after micro-needling of 3D skin models while maintaining the treatment's immunostimulatory benefits, potentially optimizing aftercare and reducing patient recovery time.
June 2024 in “International journal of nanomedicine”
This study highlights that current research efforts to deliver anti-acne drugs to hair follicles have primarily targeted healthy follicles, overlooking the distinct characteristics of pathologically clogged follicles in acne vulgaris.
June 2020 in “Journal of Investigative Dermatology”
This study found that spatial transcriptomics can reveal hidden inflammation patterns in atopic dermatitis by correlating epidermal and dermal gene expression levels, improving understanding of skin pathology.
The efficacy of microneedling for hair regrowth as either a stand-alone therapy or adjunct to Minoxidil, and whether Tretinoin is a safer and more effective option. Replies include personal accounts from users who have had success with microneedling in combination with minoxidil and peptide serums, as well as considerations of technique, depth, and potential scarring.
Hair loss is often linked to inflammation and DHT, with treatments like finasteride, dutasteride, and minoxidil being effective for many. Natural remedies like turmeric and oils are discussed, but medications are generally seen as more reliable for managing genetic hair loss.
Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.
Hair loss may be influenced by mechanical tension and inflammation, with the hi-c5 protein amplifying androgen effects, leading to follicle miniaturization. Treatments like finasteride, minoxidil, and scalp massages are suggested to manage hair loss.
DHT promotes beard growth but causes scalp hair loss due to inflammation and fibrosis. Treatments like finasteride and minoxidil help with hormonal signals and blood flow but don't address underlying inflammation.