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This study found that micro-needling with cosmeceuticals or platelet-rich plasma significantly improved wrinkles, skin laxity, scar softening, and hair growth over 12 months, with minimal side effects, and that the best results occur with pigment and platelet massaging between 5 to 30 minutes post-treatment.

This study suggests that microneedling may be an effective and less painful treatment for vitiligo, offering benefits over traditional needle injections, particularly in challenging-to-treat areas like the extremities or stubborn regions.

This study found that combining platelet-rich plasma with microneedling and subcision was effective in treating atrophic acne scars in over 80% of patients with minimal adverse effects.

This study found that using an electrical microneedling device enhanced the penetration of liposomal melanin-fluorescein into hair structures and widened the follicular infundibulum in ex vivo human skin models.

This study evaluated microneedling's effect on hair loss, finding a minor reduction in SALT scores for androgenetic alopecia patients, but no significant change for fibrosing or alopecia areata groups. Further skin biopsy analyses are pending to explore other changes beyond SALT scores.