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research Adipose Inositol Monophosphate Metabolism Is Associated with Fasting Regimen-Elicited Metabolic Benefits

October 2025 in “Biomolecules”

This study found that prolonged intermittent fasting in diet-induced obese mice led to increased levels of inositol monophosphates in white adipose tissue, improved insulin sensitivity, and reduced body weight and fat mass, suggesting a novel metabolic adaptation mechanism.

A Comprehensive Narrative Review on the Health Benefits of Apples and Their Derivatives: Focus on Cardiovascular Disease Prevention, Metabolic Regulation, and Chronic Disease Mitigation

research A Comprehensive Narrative Review Designed to Evaluate the Health Benefits of Apples and Their Derivatives, with a Focus on Cardiovascular Disease (CVD) Prevention, Metabolic Regulation, and Chronic Disease Mitigation

October 2025 in “International Journal For Multidisciplinary Research”

This review describes evidence suggesting regular apple consumption may improve cardiovascular health and reduce risks for chronic diseases through antioxidant, anti-inflammatory, and other beneficial effects, particularly when consumed as whole fruits rather than processed forms.

research Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α

June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

In male mice and rats, this study found that 17α-estradiol improves metabolic health by acting through estrogen receptor α, suggesting a potential target for treating chronic diseases in male mammals.

research Recent Perspectives on the Physiological and Therapeutic Benefits ofPlacental Extracts in Chronic Noninfectious Diseases and Aging

May 2026 in “Current Medicinal Chemistry”

This systematic review suggests that human placental extracts may offer therapeutic benefits for non-communicable diseases such as liver pathologies and metabolic disorders, but larger trials are needed to confirm efficacy and understand molecular pathways.

research DEVELOPMENT OF GARCINIA CAMBOGIA ENRICHED NUTRI BITE FOR THE MANAGEMENT OF PCOS

February 2020 in “International Journal of Advanced Research”

This article discusses the development of a Garcinia Cambogia enriched snack intended for managing PCOS but reports no new clinical results.

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community Update about Hair Follicle Glucose Metabolism: New Clinical Data Collection with Ex-President Of American Board Of Hair Restoration Surgery.

39 upvotes 2 years ago

David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

community Sublingual Minoxidil - Cure to Hairloss?

in Minoxidil 583 upvotes 2 years ago

The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.

community You NEED this if You’re Taking Fin/Dut

in Finasteride/Dutasteride 1 year ago

DIM is suggested to help with estrogen metabolism for those on finasteride or dutasteride, potentially reversing side effects like fat gain and mood changes. Some users doubt its effectiveness, recommending lifestyle changes or consulting a doctor instead.

community Finasteride is save in the eu (they concluded the investigation)

in Finasteride/Dutasteride 335 upvotes 1 year ago

Finasteride and dutasteride are still available in the EU, with a warning about potential suicidal thoughts. The benefits of these treatments are deemed greater than the risks.

community I'm thinking of incorporating tretinoin into my regimen after almost 4.5 years of being on min and 1 mg fin

in Minoxidil 6 upvotes 1 year ago

The conversation is about incorporating tretinoin into a hair loss regimen after using minoxidil and finasteride for years, with discussions on the effectiveness of minoxidil and the potential benefits of adding tretinoin. Users also discuss the effectiveness of oral minoxidil and other topical treatments like diclofenac and fluocinolone.

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