37 citations,
February 2010 in “Psychoneuroendocrinology” The study investigated the role of nuclear androgen receptors (ARs) in anabolic androgenic steroid (AAS) self-administration using rats with the testicular feminization mutation (Tfm) and wild-type (WT) littermates. Both Tfm and WT rats self-administered dihydrotestosterone (DHT) similarly, indicating that nuclear ARs were not essential for AAS self-administration. Additionally, hamsters showed a preference for DHT and DHT conjugated to bovine serum albumin (BSA), but not for BSA alone, suggesting that androgen self-administration might be mediated by plasma membrane receptors rather than nuclear ARs.
11 citations,
February 2016 in “Current Medicinal Chemistry” New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
10 citations,
May 2019 in “International Journal of Environmental Research and Public Health” Finasteride may cause kidney damage.
January 2018 in “Elsevier eBooks” The document explains how male reproductive hormones work and affect the body.
4 citations,
May 2019 in “Physiology & Behavior” Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.