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research MEF/KSF-Conditioned Culture Medium: An Effective Method for In Vitro Culture of Mouse Dermal Papilla Cells with Osteogenic Differentiation Potential

June 2021 in “Experimental and Therapeutic Medicine”

MEF/KSF-conditioned medium effectively grows mouse hair follicle stem cells with bone-forming potential.

research Investigating the Role of Mef2c in Hair Follicle Cycling

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

MEF2C is crucial for normal hair cycle progression.

Repurposing a Clinical Antimalarial for the Therapeutic Induction of Lethal ER Stress Targeting BRAF-Kinase Inhibitor-Resistant Malignant Melanoma

research Repurposing a Clinical Antimalarial for the Therapeutic Induction of Lethal ER Stress Targeting BRAF-Kinase Inhibitor-Resistant Malignant Melanoma

April 2016 in “Journal of Investigative Dermatology”

Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.

research Phase I Clinical Testing of Antimalarial Drugs

October 1977 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)”

Mefloquine was generally safe at 500 mg weekly, but higher doses caused nausea and diarrhea.

research EZH2-Mediated Inhibition of MicroRNA-22 Promotes Differentiation of Hair Follicle Stem Cells by Elevating STK40 Expression

12 citations , July 2020 in “Aging”

The protein EZH2 blocks microRNA-22, increasing STK40 protein, which helps hair follicle stem cells change and grow hair.

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Community Join

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community Is this regrowth? Start 03 2025

in Is this regrowth? 107 upvotes 4 months ago

The user started a hair loss treatment in March 2025 using finasteride, minoxidil, omega-3, biotin, a DHT-blocking multivitamin, and a derma roller, and is satisfied with the progress after four months. The community is impressed with the results, noting significant hair regrowth and improvement.

community 4 month progress after using topical minoxidil+finasteride

in Progress Pictures 152 upvotes 9 months ago

The user shared their 4-month progress using a topical solution of 5% minoxidil and 0.1% finasteride, reporting initial shedding that stopped after 2.5 months and noticeable regrowth, especially in the crown area. They use Glenmark Hair4U F from India and have experienced no side effects.

community Watching my 23 y/o self deciding to do nothing about his thinning hair

in Satire 1037 upvotes 3 years ago

Hair loss and the various treatments available, including finasteride, minoxidil, dutasteride, dermarolling, RU58841, mesotherapy, Rogaine, and scalp massages. The discussion also includes regret for not starting treatment earlier and advice to start early in order to avoid further balding.